Background: The combined orthodontic regenerative therapy approach can greatly enhance periodontal conditions and dentofacial aesthetics in many situations. The purpose of this study was to evaluate the effectiveness of 940nm low-level diode laser biostimulation in enhancement of intrabony wound healing with combined orthodontic/regenerative therapy in chronic periodontitis subjects suffering from malocclusion.
Methods: Fifteen chronic periodontitis adult patients with at least two intrabony defects and requiring orthodontic treatment for abnormalities in occlusion were included. A total of 30 defects were divided into two groups and treated in a split mouth design. The defects were treated with combined orthodontic regenerative therapy with laser irradiation (Group I: test group) or with combined orthodontic regenerative therapy alone (Group II: control group). The following hard and soft tissue measurements were recorded at baseline (prior to surgery) and after six and nine months postoperatively: probing depth (PD), clinical attachment level (CAL) by periodontal calibrated probe and bone density (BD) using the DBS-Win software.
Results: Probing depth reduction was 64.57%±9.37 and 64.95%±10.07 with no statistically significant difference between Group I and Group II. Percent change in clinical attachment level gain were 59.77%±12.107and 38.83%±7.56 in Group I and II respectively, with a statistically signifi cant difference (P-value =0.005considered signifi cant). Moreover, defects treated with combined orthodontic regenerative therapy with laser irradiation showed signifi cant preservation of bone density with a percent decrease of 4.14%±3.17 at the end of the study period.
Conclusion: Improvements in clinical and radiographic parameters were observed following the adjunctive use of low-level diode laser therapy and orthodontic regenerative therapy for the management of intrabony defects in chronic periodontitis patients.
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J Dent Sci
January 2025
Department of Dentistry, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Background/purpose: Orthodontic movement is often necessary for periodontally compromised patients to enhance esthetics, function, and long-term occlusal stability. However, the impact of orthodontic treatment immediately following the regeneration of intrabony defects on periodontal healing remains a topic of debate. The objective of this long-term case series study was to test the hypothesis that orthodontic treatment performed immediately after regenerative procedures for periodontal intrabony defects did not adversely affect periodontal healing.
View Article and Find Full Text PDFJ Nanobiotechnology
January 2025
Orthodontic Department, Nanjing Stomatological Hospital, Affiliated hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, Jiangsu, China.
Drug Des Devel Ther
January 2025
Department of Stomatology, China Academy of Chinese Medical Sciences, Xiyuan Hospital, Beijing, 100091, People's Republic of China.
Exosomes, small extracellular vesicles secreted by various cells, play crucial roles in the pathogenesis and treatment of oral diseases. Recent studies have highlighted their involvement in orthodontics, periodontitis, oral squamous cell carcinoma (OSCC), and hand, foot, and mouth disease (HFMD). Exosomes have a positive effect on the inflammatory environment of the oral cavity, remodeling and regeneration of oral tissues, and offer promising therapeutic options for bone and periodontal tissue restoration.
View Article and Find Full Text PDFBioengineering (Basel)
January 2025
Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124 Catania, Italy.
Orthodontic treatment aims to correct malocclusions and ensure the overall health and stability of the periodontium. The relationship between orthodontic therapy and periodontal health is intricate and multifaceted, and a comprehensive approach is often required to achieve optimal outcomes. Firstly, this article delves into the impact of orthodontic mechanics on periodontal tissues, emphasizing the importance of minimizing iatrogenic effects such as root resorption and gingival recession.
View Article and Find Full Text PDFMediators Inflamm
January 2025
Department of Otolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
Although numerous studies have focused on diagnostic biomarkers to help identify allergic rhinitis (AR), data on the characteristics of pediatric AR with different severity is limited. We aimed to compare the characteristics of pediatric AR with different severity. A total of 1054 children with AR were enrolled and classified into mild intermittent AR, mild persistent AR, moderate-to-severe intermittent AR, and moderate-to-severe persistent AR.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!