AI Article Synopsis
- - Infectious endocarditis affects about 43,000 people each year in the U.S., and while the modified Duke Criteria for diagnosis are not very sensitive, new imaging technologies are improving diagnostic accuracy.
- - Drug users face unique challenges in treatment due to untreated addiction and a higher risk of recurrent infections post-surgery; thus, expanding access to opioid treatment is crucial.
- - Recent research shows that oral and depo antibiotics could be effective alternatives to traditional IV therapy, and shorter antibiotic courses might be just as effective for surgically treated patients, highlighting the need for multidisciplinary care teams.
Article Abstract
Infectious endocarditis is a highly morbid disease with approximately 43,000 cases per year in the United States. The modified Duke Criteria have poor sensitivity; however, advances in diagnostic imaging provide new tools for clinicians to make what can be an elusive diagnosis. There are a number of risk stratification calculators that can help guide providers in medical and surgical management. Patients who inject drugs pose unique challenges for the health care system as their addiction, which is often untreated, can lead to recurrent infections after valve replacement. There is a need to increase access to medication-assisted treatment for opioid use disorders in this population. Recent studies suggest that oral and depo antibiotics may be viable alternatives to conventional intravenous therapy. Additionally, shorter courses of antibiotic therapy are potentially equally efficacious in patients who are surgically managed. Given the complexities involved with their care, patients with endocarditis are best managed by multidisciplinary teams.
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| http://dx.doi.org/10.1016/j.amjmed.2019.08.022 | DOI Listing |
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