Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41390-019-0575-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
BGCSL: An unsupervised framework reveals the underlying structure of large-scale whole-brain functional connectivity networks.
Comput Methods Programs Biomed
January 2025
Shanghai Maritime University, Shanghai 201306, China. Electronic address:
Background And Objective: Inferring large-scale brain networks from functional magnetic resonance imaging (fMRI) provides more detailed and richer connectivity information, which is critical for gaining insight into brain structure and function and for predicting clinical phenotypes. However, as the number of network nodes increases, most existing methods suffer from the following limitations: (1) Traditional shallow models often struggle to estimate large-scale brain networks. (2) Existing deep graph structure learning models rely on downstream tasks and labels.
View Article and Find Full Text PDFConnecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity.
Nat Commun
January 2025
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Identifying cell types and brain regions critical for psychiatric disorders and brain traits is essential for targeted neurobiological research. By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. Extrapolation of cell-type results to brain regions reveals the whole-brain impact of schizophrenia genetic risk, with subregions in the hippocampus and amygdala exhibiting the most significant enrichment of SNP-heritability.
View Article and Find Full Text PDFSuccessful thoracoscopic-assisted resection of a functional paraganglioma in the mediastinum with extracorporeal circulation: a case report.
J Cardiothorac Surg
January 2025
Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, P. R. China.
Background: Paragangliomas are rare neoplasms arising from extra-adrenal chromaffin cells, with mediastinal paragangliomas representing an exceptionally rare subset. This report details the surgical management of a complex mediastinal paraganglioma case, presenting with refractory hypertension and invasion of critical surrounding structures. A comprehensive review of the current literature is included to underscore existing cases, enhance clinical awareness, and share our insights and experience in the diagnosis and treatment of this challenging condition.
View Article and Find Full Text PDFThe first case of esophageal mediastinal fistula after immunotherapy for non-small cell lung cancer: case report and literature review.
J Cardiothorac Surg
January 2025
Department of Traditional Chinese Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Background: Malignant esophageal mediastinal fistula is a severe complication that occurs in both the advanced stages of esophageal cancer and after radiotherapy for esophageal cancer. Esophageal mediastinal fistula is very susceptible to complications such as mediastinitis and mediastinal abscess, resulting in a significantly elevated mortality rate for patients. We reported a rare case of esophageal mediastinal fistula after immunotherapy for non-small cell lung cancer (NSCLC).
View Article and Find Full Text PDFDevelopment and Application of a Polycationic Soybean Protein-Based Flocculant for Enhanced Flocculation and Dewatering of Dairy Manure.
Chemosphere
January 2025
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California-Davis, USA.
In agricultural and waste management systems, dairy manure wastewater is often recycled for irrigation. However, a key challenge lies in handling suspended solids (SS) and effectively dewatering sludge. To address this, an innovative polycationic soybean protein-based flocculant (SPI+) was developed and applied to enhance flocculation and sludge dewatering efficiency.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!