Background: There are both environmental and genetic factors which are associated with multiple sclerosis (MS) development. The primary objective of this study was to examine the predictors associated with people's attitudes towards second hand smoke exposure being a risk factor for development of MS.
Methods: The data set was drawn from the Health Canada: Smoking Survey conducted in 2004 and 2005 by Environics Research Group in partnership with Health Canada to survey the public in the province of British Columbia (N = 1468), Newfoundland (N = 1442), Quebec (N = 1404), Ontario (N = 1443) and Saskatchewan (N = 1413). A multilevel mixed effects logistic regression model analysis was carried out in order to determine whether people's perceptions of second hand smoking as a risk factor for MS varied based on the province of residence.
Results: Age, sex, having a household member who smoked inside their home, if respondents were bothered by second hand smoke exposure and smoking status were associated with increased odds of people agreeing to second hand smoke exposure being a risk factor for MS development. The province of residence was also a factor in people's perceptions.
Conclusion: The study results could guide in the development of stop second hand smoking campaigns on social media, TV and bus stop shelters and enforcement of stricter policies on smoking areas. This could help raise awareness about the risk of second hand smoking and its detrimental effect on people living with MS.
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http://dx.doi.org/10.1016/j.msard.2019.101383 | DOI Listing |
Anal Chem
January 2025
State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.
As the most common and lethal cancer of the female gonads, ovarian cancer (OC) has a grave impact on people's health. OC is asymptomatic, insidious in onset, difficult to diagnose and treat, fast-growing, and easy to metastasize and has poor prognosis and high mortality. How to detect OC as early as possible and treat it without side effects has become a challenging medical problem.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Geriatrics, The Third People's Hospital of Yunnan Province, The Second Affiliated Hospital of Dali University, 292 Beijing Road, Kunming, 650011, Yunnan Province, China.
Sarcopenia is an age-related muscle senescence disease that leads to functional limitations, physical disability and premature death in older adults. Atherogenic index of plasma (AIP) is a novel indicator of atherosclerotic status based on triglycerides and high-density lipoprotein cholesterol. The aim of this study was to investigate the association between AIP and new-onset sarcopenia and its components among middle-aged and older adults in a Chinese community.
View Article and Find Full Text PDFHand Surg Rehabil
January 2025
Centre Hospitalier Régional Universitaire de Nîmes, Department of Orthopaedic Surgery, Nîmes, France.
Dynamic compression of the median nerve under the lacertus fibrosus at the elbow causes pain and weakness. It is a frequently overlooked pathology and a cause of failed recovery after carpal tunnel release. The purpose was to present a technical note on minimally invasive ultrasound-guided lacertus syndrome surgical treatment under WALANT.
View Article and Find Full Text PDFPeptides
January 2025
Department of Hand and Foot Surgery, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250033, China. Electronic address:
Delayed wound healing is a complication of diabetes mellitus and can lead to infection, sepsis, and amputation. Despite the currently available treatments, the global burden of diabetes-related wounds is growing; thus, more effective therapy for diabetic wounds is urgently needed. Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is a 28-amino acid peptide hormone.
View Article and Find Full Text PDFDrug Resist Updat
January 2025
Loma Linda University Cancer Center, Loma Linda, CA 92354, United States; Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, United States. Electronic address:
Chromosomal rearrangements (CR) initiate leukemogenesis in approximately 50 % of acute myeloid leukemia (AML) patients; however, limited targeted therapies exist due to a lack of accurate molecular and genetic biomarkers of refractory mechanisms during treatment. Here, we investigated the pathological landscape of treatment resistance and relapse in 16 CR-AML patients by monitoring cytogenetic, RNAseq, and genome-wide changes among newly diagnosed, refractory, and relapsed AML. First, in FISH-diagnosed KMT2A (MLL gene, 11q23)/AFDN (AF6, 6q27)-rearrangement, RNA-sequencing identified an unknown CCDC32 (15q15.
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