Individualized mating system estimation using genomic data.

Mol Ecol Resour

Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS, USA.

Published: January 2020

The estimation of outcrossing rates in hermaphroditic species has been a major focus in the evolutionary study of reproductive strategies, and is also essential for plant breeding and conservation. Surprisingly, genomics has thus far minimally influenced outcrossing rate studies. In this article, we generalize a Bayesian inference method (BORICE) to accommodate genomic data from multiple subpopulations of a species. As an empirical demonstration, BORICE is applied to 115 maternal families of Mimulus guttatus. The analysis shows that low-level whole genome sequencing of parents and offspring is sufficient for individualized mating system estimation: 208 offspring (88.5%) were definitively called as outcrossed, 23 (9.8%) as selfed. After mating system parameters are established (each offspring as outcrossed or selfed and the inbreeding level of maternal plants), BORICE outputs posterior genotype probabilities for each SNP genomewide. Individual SNP calls are often burdened with considerable uncertainty and distilling information from closely linked sites (within genomic windows) can be a useful strategy. For the Mimulus data, principal components based on window statistics were sufficient to diagnose inversion polymorphisms and estimate their effects on spatial structure, phenotypic and fitness measures. More generally, mating system estimation with BORICE can set the stage for population and quantitative genomic analyses, particularly researchers collect phenotypic or fitness data from maternal individuals.

Download full-text PDF

Source
http://dx.doi.org/10.1111/1755-0998.13094DOI Listing

Publication Analysis

Top Keywords

mating system
16
system estimation
12
individualized mating
8
genomic data
8
phenotypic fitness
8
system
4
estimation
4
genomic
4
estimation genomic
4
data
4

Similar Publications

Male reproductive proteins frequently evolve rapidly in animals, potentially due to adaptive evolution driven by sperm competition, polyspermy avoidance, or pathogen defense. Alternatively, elevated rates of protein change may be due to relaxed constraint. The prostate-specific protease KLK3 has experienced dynamic evolution since its origin stemming from a gene duplication in the ancestor of all Old World primates, with instances of rapid evolution, stasis, and pseudogenization.

View Article and Find Full Text PDF

Mating system of a vector of .

Curr Res Parasitol Vector Borne Dis

January 2025

Western University of Health Sciences, 200 Mullins Dr, Lebanon, OR, 97355, USA.

snails are intermediate hosts for schistosome parasites, which cause morbidity and mortality in humans worldwide. We aimed to determine the mating system of , a hermaphroditic vector of schistosomiasis in the African Great Lakes, with the goal of informing the design of genetic studies such as linkage mapping to improve genome assembly and genetic association studies to identify snail resistance genes. To determine the relative rates of outcrossing selfing, we assayed the progeny of experimental crosses of snails in the laboratory using a PCR and restriction enzyme digest to determine snail genotype and parentage.

View Article and Find Full Text PDF

Major changes in genetic variation are generally considered deleterious to populations. The massive biodiversity of insects distinguishes them from other animal groups. Insect deviant effective population sizes, alternative modes of reproduction, advantageous inbreeding, endosymbionts, and other factors translate to highly specific inbreeding and outbreeding outcomes.

View Article and Find Full Text PDF

Evolutionary changes in development and/or host number of parasite life cycles can have subsequent ecological and evolutionary consequences for parasites. One theoretical model based on the mating systems of hermaphroditic parasites assumes a life cycle with fewer hosts will result in more inbreeding, and predicts a truncated life cycle most likely evolves in the absence of inbreeding depression. Many populations of the hermaphroditic trematode Alloglossidium progeneticum maintain an ancestral obligate 3-host life cycle where obligate sexual reproduction occurs among adults in catfish third hosts.

View Article and Find Full Text PDF

Evaluation of frictional wear in a follow-up screw-rod kinematic node in GGS transpedicular stabilization.

Acta Bioeng Biomech

September 2024

Department of Mechanics, Materials and Biomedical Engineering, Faculty of Mechanical Engineering, Wrocław University of Science and Technology, Wrocław, Poland.

: The aim of this study was to evaluate the abrasive wear of the sliding screw-rod joint used in growth guidance system (GGS) stabilizers, allowing for the translation of the screw along the rod during the spinal growth process in a standard and modified system. : The study used single kinematic screw-rod pairs made of titanium alloy Ti6Al4V. Mechanical tests (cyclic loads) simulated the stabilizer's operation under conditions similar to actual use.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!