AI Article Synopsis
- Fragmented QRS (fQRS) on ECG is linked to intramyocardial conduction delays from ventricular scarring, particularly in patients with persistent atrial fibrillation (PsAF).
- A study involving 376 PsAF patients found that those with fQRS exhibited significantly higher rates of both any degree and severe left atrial (LA) scarring.
- fQRS serves as a valuable and noninvasive predictor of severe LA scarring and recurrent atrial arrhythmias in these patients, indicating its potential use in clinical settings.
Article Abstract
Background: Fragmented QRS (fQRS) on 12-lead electrocardiography is a noninvasive marker of intramyocardial conduction delay due to ventricular scarring that has not previously been studied in atrial fibrillation.
Objective: The purpose of this study was to assess the association of fQRS with left atrial (LA) scarring in patients with persistent atrial fibrillation (PsAF) undergoing first catheter ablation.
Methods: A total of 376 patients with PsAF were enrolled. Severity of LA scarring was assessed using electroanatomic mapping. Narrow fQRS was defined by the presence of an additional R wave (R') or notching in the nadir of the S wave, or the presence of >1 R' in 2 contiguous leads corresponding to inferior, lateral, or anterior myocardial regions.
Results: Both any degree (97.3% vs 63.3%) and severe (42.2% vs 6.3%) LA scarring were higher in patients with fQRS. Age and fQRS were found to be independent predictors of severe LA scarring. At multiple ventricular regions, fQRS had diagnostic accuracy of 79.8% for prediction of severe LA scarring. Nonpulmonary vein triggers were more often detected and ablated in patients with fQRS and severe LA scarring (84.4% vs 70%; P = .001). Atrial tachyarrhythmia recurrence was observed in 131 patients (34.8%) during 18.9 ± 7.7 months of follow-up, which was significantly higher in patients with fQRS (53.2% vs 16.8%). In multivariate analysis, fQRS was found to be a significant predictor of recurrence (hazard ratio 4.65; 95% interval confidence 2.91-7.42; P <.001).
Conclusion: The study results showed that fQRS is a simple, available, and noninvasive marker, and that fQRS at multiple ventricular regions is significantly associated with the severity of LA scarring in PsAF patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.hrthm.2019.09.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Electrocardiographic Frontal QRS-T Angle Is Independently Associated with the Presence of Celiac Disease and Disease Duration.
Diagnostics (Basel)
January 2025
Department of Cardiology, Faculty of Medicine, Gazi University, 06560 Ankara, Turkey.
The impact of Celiac Disease (CD) is not only limited to the intestinal system, but extraintestinal manifestations may also be seen. In this context, cardiac manifestations have recently been the focus of attention. This study aimed to evaluate myocardial repolarization properties in CD patients by assessing the frontal QRS-T Angle (fQRS-T) on electrocardiography (ECG).
View Article and Find Full Text PDFIncreased para-aortic adipose tissue on echocardiography may closely be related with fragmented QRS.
Colomb Med (Cali)
January 2025
Karabuk University Faculty of Medicine, Department of Cardiology, Karabuk, Turkey Karabük University Karabuk University Faculty of Medicine Department of Cardiology Karabuk Turkey.
Background: The association of fragmented QRS (fQRS) with many cardiac pathologies such as cardiac fibrosis has been described previously. Paraaortic adipose tissue (PAT) is thought to be associated with many cardiac diseases and there is only one publication on its echocardiographic evaluation.
Aims: To describe the possible relationship between fQRS and PAT.
A Novel Electrocardiographic Marker for Predicting Total Mortality in Ischemic Stroke: Frontal QRS-T Angle.
Turk Kardiyol Dern Ars
January 2025
Department of Cardiology, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, İstanbul, Türkiye.
Objective: This study aimed to investigate the relationship between mortality and the frontal QRS-T angle (FQRS-TA), obtained by calculating the absolute difference between the QRS and T waves electrocardiographically (ECG), in patients diagnosed with ischemic stroke (IS).
Methods: This research is a retrospective and cross-sectional study. The diagnosis of IS was confirmed through brain imaging and physical examination.
AI-enabled detection of QRS fragmentation from 12-lead electrocardiogram and its clinical relevance for predicting malignant arrhythmia onset.
Front Cardiovasc Med
October 2024
Department of Cardiovascular Sciences, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Background: Electrocardiographic markers differentiating between death caused by ventricular arrhythmias and non-arrhythmic death could improve the selection of patients for implantable cardioverter-defibrillator (ICD) implantation. QRS fragmentation (fQRS) is a parameter of interest, but subject to debate. We investigated the association of an automatically quantified probability of fragmentation with the outcome in ICD patients.
View Article and Find Full Text PDFElectrocardiographic correlates of cardiac magnetic resonance findings in women with myocardial infarction with non-obstructive coronary arteries.
J Electrocardiol
December 2024
Sarah Ross Soter Center for Women's Cardiovascular Research, Leon H. Charney Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, NY, United States of America. Electronic address:
Background: Myocardial infarction with nonobstructive coronary arteries (MINOCA) occurs in 6-15 % of MI patients. Cardiac magnetic resonance (CMR) imaging identifies MINOCA etiologies, but access may be limited.
Methods: We assessed associations between the index electrocardiogram (ECG) and CMR in MINOCA.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!