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[Flavonoids – natural compounds with antiviral and anticancer potential].
Postepy Biochem
December 2024
Katedra Biotechnologii, Wydział Nauk Biologicznych, Uniwersytet Zielonogórski.
Flavonoids are a group of plant secondary metabolites that have a number of health-promoting properties and have both preventive and therapeutic effects. Research confirms that flavonoids work, among others: antiviral and anticancer. Apigenin, luteolin, isorhamnetin, kaempferol, myricetin, quercetin, hesperetin, naringenin, epicatechin and genistein have documented antiviral activity.
View Article and Find Full Text PDFWilld., Source of Antioxidants with Diverse Chemical Structures.
Molecules
December 2024
Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343 Kraków, Poland.
Ethanolic extracts from the roots and aerial parts of the hitherto chemically uninvestigated lettuce species Willd. (Cichorieae, Asteraceae) were chromatographically separated to obtain eight sesquiterpenoids, two apocarotenoids (loliolide and (6,9) roseoside), and three phenolic glucosides (apigenin 7--glucoside, eugenyl-4---glucopyranoside, and 5-methoxyeugenyl-4---glucopyranoside). Four of the isolated sesquiterpene lactones (8--angeloyloxyleucodin, matricarin, 15-deoxylactucin, and deacetylmatricarin 8--glucopyranoside) have not previously been found either in spp.
View Article and Find Full Text PDFMechanisms and early efficacy data of caloric restriction and caloric restriction mimetics in neurodegenerative disease.
Neuroscience
January 2025
Department of Biosciences, Jamia Millia Islamia, New Delhi, 110025, India; Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Karnataka, Manipal, 576 104, India. Electronic address:
Neurodegenerative disorders (NDDs) have been prevalent for more than a decade, and the number of individuals affected per year has increased exponentially. Among these NDDs, Alzheimer's disease, which causes extreme cognitive impairment, and Parkinson's disease, characterized by impairments in motor activity, are the most prevalent. While few treatments are available for clinical practice, they have minimal effects on reversing the neurodegeneration associated with these debilitating diseases.
View Article and Find Full Text PDFApigenin as an emerging hepatoprotective agent: current status and future perspectives.
Front Pharmacol
December 2024
School of Clinical Medical, Chengdu Medical College, Chengdu, China.
Apigenin (CHO, API) is a natural flavonoid widely found in vegetables, fruits, and plants such as celery, oranges, and chamomile. In recent years, API has attracted considerable attention as a dietary supplement due to its low toxicity, non-mutagenic properties and remarkable therapeutic efficacy in various diseases. In particular, evidence from a large number of preclinical studies suggests that API has promising effects in the prevention and treatment of a variety of liver diseases, including multifactorial liver injury, non-alcoholic fatty liver disease/non-alcoholic steatohepatitis, liver fibrosis and liver cancer.
View Article and Find Full Text PDFEffects of Coix seed polyphenol extract on rumen fermentation, milk production, fatty acid profile, antioxidant activity, and polyphenol content in dairy goats.
J Dairy Sci
December 2024
Laboratory of Animal Genetics, Breeding and Reproduction in the Plateau Mountainous Region, Ministry of Education, College of Animal Science, Guizhou University, Guiyang, 550025, Guizhou, P.R. China. Electronic address:
The transfer of natural antioxidants from feed to milk has become a research hotspot. Polyphenols are a source of potent natural antioxidants that may play important roles in improving antioxidant activity and milk quality in dairy goats. The aim of this study was to evaluate the effects of polyphenol-rich Coix seed extract (CSE) on rumen fermentation, milk production, fatty acid profile, antioxidant activity, and polyphenol content in milk from lactating dairy goats.
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