AI Article Synopsis
- This study presents a new method for intramolecular C-H amination of sulfamate esters without using transition metals, utilizing iodine oxidants like tert-butyl hypoiodite (t-BuOI) and N-iodosuccinimide (NIS).
- The method with NIS is effective not only for sulfamate esters but also for the oxidative cyclization of N-alkylsulfamides.
- This research offers a potential alternative for C-H amination reactions in organic synthesis.
Article Abstract
The transition-metal-free intramolecular C-H amination of sulfamate esters using iodine oxidants, tert-butyl hypoiodite (t-BuOI) and N-iodosuccinimide (NIS) is reported. A method using NIS was also successfully applied to the oxidative cyclization of N-alkylsulfamides.
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| http://dx.doi.org/10.1039/c9cc06410a | DOI Listing |
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