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Association of statins, gliptins, and antipsychotics with bullous pemphigoid: A case-control study in the Cretan population.
J Dermatol
January 2025
School of Medicine, University of Crete, Heraklion, Greece.
Bullous pemphigoid (BP) is an autoimmune blistering disorder predominantly affecting the elderly. Recently, many studies have shed light on the effect of specific drug intake and comorbidities on the development of BP. The purpose of this study was to investigate the association of specific drug class intake and comorbidities with the development of BP in the Cretan population.
View Article and Find Full Text PDFEvaluation of link between COVID-19 adjacent spike in hydroxychloroquine use and increased reports of pemphigus: a disproportionality analysis of the FDA Adverse Event Reporting System.
Front Immunol
January 2025
Department of Dermatology, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, United States.
Importance: Identifying environmental factors that contribute to disease onset/activity in PV stands to improve clinical outcomes and patient quality of life by strategies aimed at reducing specific disease promoting exposures and promoting personalized clinical management strategies.
Objective: To evaluate the association between hydroxychloroquine use and the development of pemphigus using population level, publicly available, FDA-generated data.
Design: Observational, retrospective, case-control, pharmacovigilance analysis.
A Narrative Review of Molecular, Immunohistochemical and In-Situ Techniques in Dermatopathology.
Br J Biomed Sci
January 2025
St. John's Dermatopathology Laboratory, Synnovis Analytics, St. Thomas' Hospital, London, United Kingdom.
Article Synopsis
- Skin disorders are a major global health issue, affecting millions and requiring improved understanding and treatment approaches.
- Recent advancements in molecular techniques, like PCR and next-generation sequencing, have enhanced our ability to diagnose and treat these disorders accurately and effectively.
- These technologies allow for precise identification of infectious agents, genetic mutations, and gene expression patterns, leading to personalized therapies and better management of conditions like skin cancer and infections.
Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review.
Oman Med J
July 2024
Family Medicine General Foundation Program, Oman Medical Specialty Board, Muscat, Oman.
We report a rare case of a middle-aged Omani woman who was known to have primary antiphospholipid syndrome, glucose-6-phosphate dehydrogenase deficiency, and iron deficiency anaemia. Cannulation attempts caused bulla which progressed to ulceration. A pathergy phenomenon with high suspicion of pyoderma gangrenosum was postulated.
View Article and Find Full Text PDFAn Unusual Presentation of Cutaneous Bullous Lupus.
Cureus
November 2024
Rheumatology, Cooper University Health Care, Camden, USA.
Drug-induced lupus erythematosus (DILE) is an autoimmune reaction that results in symptoms of polyarthralgia, fever, and cutaneous lesions and other manifestations. Several drugs have been documented to cause this disease, including procainamide, isoniazid, methyldopa, penicillamine, and hydralazine. Systemic lupus erythematosus (SLE) manifestations often occur after the patient has been taking the drug without complications for months to years.
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