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is rarely associated with neurological manifestations. This report describes a rare case of endocarditis complicated by a cerebral stroke caused by . We also briefly reviewed the neurological clinical spectrum of disease described in the literature.
View Article and Find Full Text PDFIntegrating Diagnostic Approaches in Infant Bacterial Meningitis Caused by a Non-K1 : A Case Report.
Antibiotics (Basel)
November 2024
Microbiology and Diagnostic Immunology Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Background: Infant meningitis, particularly caused by , remains a life-threatening condition, especially in premature and low-weight infants. Infections of the central nervous system can be fatal, necessitating prompt diagnosis and appropriate treatment. Acute infections caused by various pathogens, including , often present with similar clinical symptoms.
View Article and Find Full Text PDF[Rapid Diagnosis of Central Nervous System Infections by Multiplex PCR Assay and the Viral Etiology in Children].
Mikrobiyol Bul
October 2024
University of Health Sciences, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Clinic of Pediatric Infectious Diseases, İzmir, Türkiye.
Article Synopsis
- The study investigates the effectiveness of syndromic tests for diagnosing central nervous system (CNS) infections in children, highlighting the urgency of timely diagnosis.
- A total of 145 pediatric patients were analyzed, revealing that viral pathogens were the most common cause of CNS infections among those tested, with bacterial and no fungal infections detected.
- The use of syndromic tests significantly reduced diagnostic turnaround time, which averaged around 2 hours, and aided in guiding appropriate treatment for affected children.
Comparison of positive BioFire FilmArray meningitis/encephalitis (ME) panels, CSF cultures, CSF parameters, clinical presentation and in-patient mortality among patients with bacterial and fungal meningitis.
Microbiol Spectr
December 2024
Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky, USA.
Unlabelled: The BioFire FilmArray meningitis/encephalitis panel (MEP) was brought to the University of Kentucky in 2016 to aid in the identification of community-acquired meningitis and encephalitis (ME). This panel has shown variable performance with some institutions showing high sensitivity and specificity for many pathogens but others seeing false positives during clinical use. We evaluated the panel's performance using retrospective chart review of patients at the University of Kentucky from October 2016 to September 2022, including 7,551 MEP results.
View Article and Find Full Text PDFEpidemiological, Biological, and Clinical Characteristics of Central Nervous System Enterovirus Infections Among Hospitalized Patients at Ibn Sina University Hospital Center in Rabat: Case Study Report (A Series of 19 Cases).
Adv Virol
November 2024
Mohammed V University in Rabat, Faculty of Medicine and Pharmacy, Rabat, Morocco.
Article Synopsis
- Enterovirus infections can impact the central nervous system, causing conditions like meningitis and encephalitis, and this study aimed to detail these infections for Moroccan patients.
- Conducted from January 2021 to March 2023 at Ibn Sina University Hospital, the study analyzed 1,479 cerebrospinal fluid samples, finding enterovirus in just 19 patients, mostly young children and males.
- Common symptoms included fever and headache, and while many cases showed lymphocytic patterns in CSF analysis, some results could mimic bacterial infections, highlighting the importance of using multiplex PCR for accurate diagnosis.
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