The Role of Risk Prediction Models in Prevention and Management of AKI.

Semin Nephrol

Intensive Care Department, The Royal Surrey County Hospital National Health Service Foundation Trust, Guildford, United Kingdom; Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University of Surrey, Guildford, United Kingdom. Electronic address:

Published: September 2019

Acute kidney injury is a major health care problem. Improving recognition of those at risk and highlighting those who have developed AKI at an earlier stage remains a priority for research and clinical practice. Prediction models to risk-stratify patients and electronic alerts for AKI are two approaches that could address previously highlighted shortcomings in management and facilitate timely intervention. We describe and critique available prediction models and the effects of the use of AKI alerts on patient outcomes are reviewed. Finally, the potential for prediction models to enrich population subsets for other diagnostic approaches and potential research, including biomarkers of AKI, are discussed.

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http://dx.doi.org/10.1016/j.semnephrol.2019.06.002DOI Listing

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