AI Article Synopsis
- The management of chronic urticaria (CU) is inconsistent among dermatologists, despite updated international guidelines suggesting evidence-based treatment approaches.
- A survey of 165 dermatologists in Argentina showed that only 50% used optimal first-line treatments, with even lower percentages for second-line (35%) and third-line (15%) treatments.
- Factors such as being older than 55 years and having more than 5 years of experience were linked to suboptimal second-line treatment, indicating that real-life CU management in Argentina often does not align with international standards.
Article Abstract
The management of chronic urticaria (CU) has been controversial. Recently updated international guidelines propose evidence-based diagnosis and treatment. Nevertheless, dermatologists have heterogeneous approaches to managing CU. To estimate the percentage of dermatologists who have an optimal approach to CU according to the international guidelines, and to explore the variables associated with optimal management a cross-sectional study using a 17-question survey was delivered by email to dermatologists from Argentina. Optimal first, second, and third line treatment were considered when dermatologists chose a nonsedative antihistamine; increased the dosage of nonsedative antihistamines, and added omalizumab, respectively. Logistic regression was used to identify variables associated with optimal management. A total of 165 questionnaires were available for analysis. An optimal first, second, and third-line treatment approach was identified in 50%, 35%, and 15% of the dermatologists, respectively. The dermatologists' age being above 55 years old (OR: 0.12, 95% CI: 0.01-0.99, p .005) and having more than 5 years of expertise (OR: 0.4, 95% CI: 0.19-0.81, p .001) were significantly associated with a suboptimal approach in second-line treatment. We could not find variables associated with an optimal first or third-line treatment. The real-life management of CU in Argentina is partly suboptimal according to the international guidelines.
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| http://dx.doi.org/10.1111/dth.13086 | DOI Listing |
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