Purpose: To assess the utility and accuracy of creatinine measurement using point-of-care (POC) blood gas analysis compared to standard laboratory assay and to assess the effectiveness of frequent creatinine monitoring using POC blood gas analysis with respect to early detection of acute kidney injury (AKI).
Methods: We performed a single center retrospective observational study in 398 patients admitted to the intensive care unit. We investigated the clinical concordance of creatinine values measured by POC blood gas analysis (Cr-BG) compared to those measured by laboratory assay (Cr-lab). We compared the time to reach AKI diagnosis according to the KDIGO criteria using Cr-BG (KD-BG) to the standard criteria using Cr-lab (KD-lab).
Results: Cr-BG correlated well with Cr-lab for day 1 (n = 375, R = 0.98, p < 0.001) and during the whole study period (n = 1258, R = 0.99, p < 0.001). The KD-BG measurement allowed the identification of 6.3% more patients (60.6%) as AKI than the KD-lab measurement. Approximately one-third of the patients were staged as AKI using the KD-BG measurement more than 6 h earlier than that using the KD-lab measurement.
Conclusions: The KDIGO criteria using POC blood gas analysis were clinically useful. Frequent creatinine monitoring using POC analysis can allow an earlier detection of AKI.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s40620-019-00641-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Glycemic Management of Patients with Hospital Hyperglycemia: A Retrospective Cohort Study on Adults Admitted in the Non-ICU Wards.
Diabetes Metab Syndr Obes
January 2025
Department of Endocrinology and Metabolism, Ningbo No.2 hospital, Ningbo, Zhejiang Province, People's Republic of China.
Purpose: To identify the key populations for Hospital Hyperglycemia (HH) management and to assess recent trends in the management of HH.
Patients And Methods: This retrospective study analyzed 1,136,092 point-of-care blood glucose (POC-BG) measurements from 40,758 patients with HH in non-intensive care unit (non-ICU) wards at Ningbo No.2 hospital from January 2020 to December 2022.
Comparison of Freestyle Optium Neo H and Centrivet GK Device in the Diagnosis of Hypoglycaemia and Hyperketonaemia in Dairy Goats: A Field Study.
Vet Med Sci
January 2025
Department of Statistics, Faculty of Science, University of Muğla Sıtkı Koçman, Muğla, Turkey.
Background: There is a lack of data on the validation and diagnostic performance of the Freestyle Optium Neo-H (Freestyle) and Centrivet GK (Centrivet) devices for the diagnosis of hypoglycaemia, hyperglycaemia and hyperketonaemia in goats.
Objectives: The aim of the present study was to validate the Freestyle and Centrivet for the analysis of whole blood beta-hydroxybutyric acid (BHBA) and to validate the Freestyle for the analysis of whole blood glucose concentrations using the reference method (RM) in goat blood collected from the jugular and ear veins.
Methods: Venous blood samples were utilised to assess glucose and BHBA concentrations using the Freestyle, Centrivet and RM.
Quantitative determination of leptin hormone using gold nanoparticle-based lateral flow assay.
Mikrochim Acta
January 2025
Science and Technology Research and Application Center (BITAM), Necmettin Erbakan University, Konya, Türkiye.
A lateral flow assay (LFA) has been developed that can be used in point-of-care (PoC) use for the sensitive determination of leptin hormone. The limit of detection value was 0.158 ng/mL and the limit of quantification value was 0.
View Article and Find Full Text PDFComparison between point-of-care testing from capillary samples and conventional laboratory testing from venous samples for white blood cells and C-reactive protein in a pediatric outpatient setting.
J Gen Fam Med
January 2025
Department of Pediatrics Tsugaruhoken Medical COOP Kensei Hospital Hirosaki Aomori Japan.
Background: Studies on the accuracy of point-of-care (POC) testing using capillary samples are scarce. Therefore, this study aimed to assess the analytical accuracy of POC testing for white blood cell (WBC) and C-reactive protein (CRP) using capillary samples compared with conventional central laboratory testing using venous samples in a pediatric ambulatory care setting.
Methods: This was a retrospective study including patients younger than 18 years who underwent concurrent WBC and CRP evaluations via capillary and subsequent venous sampling within a 2-h window.
Comparison of Standard and Point-of-Care CD4+ T Lymphocyte Measurement Methods in HIV-1 Infected Turkish Patients.
Medicina (Kaunas)
December 2024
Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kocaeli University, Kocaeli 41001, Turkey.
: CD4+ T lymphocytes are the primary targets of HIV infection. CD4+ T lymphocyte count is an indicator of immune competence. In this study, we aimed to compare standard flow cytometry and point-of-care (POC) CD4+ T lymphocyte in terms of cost, effectiveness, reliability, time, and the use of this method for disease.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!