Quantitative electromyography is an important tool to evaluate myopathies, and some difficult-to-treat asthmatic patients may have a subclinical corticosteroid myopathic process, using only inhaled corticosteroid, according to some studies. In this report, diaphragm quantitative electromyography was used to evaluate asthmatic difficult-to-treat patients, comparing them with a control group. Significant differences were obtained in amplitude, duration and size index of motor unit action potentials, with lower parameters in the asthmatic patients, which may indicate a myopathic process.
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http://dx.doi.org/10.1590/0004-282X20190085 | DOI Listing |
Front Neurosci
January 2025
Neurology Associate P.C., Lincoln, NE, United States.
Introduction: As a hallmark feature of amyotrophic lateral sclerosis (ALS), bulbar involvement significantly impacts psychosocial, emotional, and physical health. A validated objective marker is however lacking to characterize and phenotype bulbar involvement, positing a major barrier to early detection, progress monitoring, and tailored care. This study aimed to bridge this gap by constructing a multiplex functional mandibular muscle network to provide a novel objective measurement tool of bulbar involvement.
View Article and Find Full Text PDFBMC Sports Sci Med Rehabil
January 2025
Universite Lyon 1, Laboratoire Interuniversitaire de Biologie de la Motricité - UR 7424, UFRSTAPS, Villeurbanne, France.
Background: The Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST) is a physical performance test designed to assess the upper extremity (UE) stability. However, only one outcome measure is provided for both UEs, limiting its application if the UEs are not similarly involved. Moreover, the changes in loads sustained by the support UE throughout the movement may influence the support UE stability.
View Article and Find Full Text PDFMov Disord
January 2025
Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Background: Quantitative evidence of levodopa-induced beneficial effects on parkinsonian rigidity in Parkinson's disease (PD) is lacking. Recent research has demonstrated the velocity-dependent nature of objective rigidity in PD and revealed its neural underpinning.
Objective: The present study aimed to examine the effect of levodopa on objective rigidity in PD.
BMJ Open Respir Res
January 2025
Lane Fox Clinical Respiratory Physiology Research Unit, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Introduction: Patients recovering from severe acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have a 30-day readmission rate of 20%. This study evaluated the feasibility of conducting a randomised controlled trial to evaluate clinical, patient-reported and physiological effects of home high-flow therapy (HFT) in addition to usual medical therapy, in eucapnic patients recovering from AECOPD to support the design of a phase 3 trial.
Methods: A mixed-methods feasibility randomised controlled trial (quantitative primacy, concurrently embedded qualitative evaluation) (ISRCTN15949009) recruiting consecutive non-obese patients hospitalised with AECOPD not requiring acute non-invasive ventilation.
J Indian Prosthodont Soc
January 2025
Department of Prosthodontics, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Aim: Aberrative occlusal contacts were associated with Temporomandibular disorder (TMD), but whether stabilization splints with therapeutic exercises alleviate the symptoms is unclear. Hence, this study aims to compare the short-term efficacy of occlusal splint therapy and the synergistic effect of therapeutic exercise with occlusal splint therapy for 3 weeks in individuals with TMD.
Settings And Design: in-vivo observational pilot study.
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