A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 143

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 209
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3098
Function: getPubMedXML

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: Attempt to read property "Count" on bool

Filename: helpers/my_audit_helper.php

Line Number: 3100

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3100
Function: _error_handler

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Challenging Diagnosis. | LitMetric

AI Article Synopsis

  • Epstein-Barr virus (EBV) primarily infects B-cell lymphocytes, often presenting with symptoms like tonsillitis and cervical lymphadenopathy, but can sometimes mimic lymphoproliferative diseases.
  • A case study of a 77-year-old woman highlights the diagnostic challenges between EBV infection and diffuse large B-cell lymphoma, despite thorough examinations.
  • Key learning points stress the risk of misdiagnosing lymphoma as EBV infection, the limitations of immunophenotypic analysis in confirming the disease type, and the importance of timely lymphoma diagnosis for effective treatment.

Article Abstract

Unlabelled: Epstein-Barr virus (EBV) is a double-stranded virus that shows tropism for B-cell lymphocytes. EBV-infected patients usually present with tonsillitis/pharyngitis, cervical lymphadenopathy and fever, but an atypical presentation can mimic lymphoproliferative disease. We present the case of a 77-year-old woman with asthenia, fever, oral ulcers and peripheral lymphadenopathy. After extensive evaluation, including anatomopathological and immunocytochemical examination of excisional lymph node biopsy samples, it was still not clear whether the patient had EBV infection or diffuse large B-cell lymphoma. In this case report, the authors describe how it can be difficult to differentiate between two different, although related, entities, making diagnosis of lymphoma highly challenging.

Learning Points: Lymph node biopsy findings may result in lymphoma being misdiagnosed as acute Epstein-Barr virus infection.Immunophenotypic analysis can occasionally be insufficient to establish the clonal nature of the disease.Timely diagnosis of lymphoma is necessary so that immunochemotherapy can be initiated and clinical improvement achieved.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726345PMC
http://dx.doi.org/10.12890/2019_001077DOI Listing

Publication Analysis

Top Keywords

large b-cell
8
b-cell lymphoma
8
epstein-barr virus
8
lymph node
8
node biopsy
8
diagnosis lymphoma
8
lymphoma
5
t-cell/histiocyte-rich large
4
lymphoma challenging
4
challenging diagnosis
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: