Standardization and Personalized Medicine Using Quantitative EEG in Clinical Settings.

Two major trends have been dominant in health care in recent years. First, there is a growing consensus that standardization of health care procedures and methods can result in improved effectiveness and safety of treatments. Second, there is increased interest in "personalized medicine," which refers to the tailoring of treatments to individual patients. Here I discuss how these trends apply to the field of quantitative EEG (qEEG), where de-artifacted resting state EEGs of individuals are compared with a normative database in order to assess clinically meaningful deviations, which can be used for diagnostic procedures, to guide personalized treatment protocols, and to assess treatment effectiveness. Standardized and automated de-artifacting procedures are increasingly being used in scientific research and in clinical practice. The advantages of these procedures over manual de-artifacting will be discussed. The results of a systematic comparison between 2 commonly used qEEG databases show that these databases produce very comparable results, illustrating not only the validity and reliability of both databases but also the opportunity to move forward to a standardized use of qEEG in clinical practice. Finally, the standardization of qEEG interpretation as both a diagnostic and treatment selection tool provides an example of how qEEG can merge both personalized medicine and standardization in the treatment of psychological disorders.