Breast metastasis of the well differentiated neuroendocrin tumor (WDNET) of the ileum is very rare. A case of a 62-year-old woman with ileal WDNET, who underwent restaging with Ga-68 DOTATATE PET/CT due to progression of metastatic lesions under the treatment with somatostatin analog and mammalian target of rapamycin inhibitors. Ga-68 DOTATATE PET/CT demonstrated intense increased uptake in the subsantimetric nodular lesion in the upper outer quadrant of the left breast. The histopathologic findings obtained by tru-cut biopsy revealed WDNET metastasis (Ki-67 proliferation index 1%).
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http://dx.doi.org/10.4274/mirt.galenos.2019.28199 | DOI Listing |
BMJ Case Rep
November 2024
Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
A patient with a long history of bone predominant, metastatic paraganglioma who had multiple episodes of progressive disease despite prior treatments demonstrated a remarkable disease response to zoledronic acid. After 1 year of treatment, there was a complete resolution of lymphadenopathy and disappearance of all somatostatin receptor avid lesions by positron emission tomography-CT and radiopharmaceutical Gallium Ga 68 Dotatate. Stability of disease was further demonstrated by CT over several years.
View Article and Find Full Text PDFClin Nucl Med
December 2024
Department of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing, China.
We present the imaging findings of a 48-year-old woman that metastasized to multiple bones with a history of duodenal gangliocytic paraganglioma. 68Ga-DOTATATE PET/CT showed multiple osteolytic bone destruction with intense uptake. Multiple bone metastases originating from duodenal gangliocytic paraganglioma confirmed histopathological results of a biopsy on the chest-back bone.
View Article and Find Full Text PDFClin Nucl Med
January 2025
Department of Nuclear Medicine, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.
Clin Nucl Med
January 2025
From the Department of Endocrinology, Seth G S Medical College.
A 42-year-old man, a known case of FGF23-dependent hypophosphatemia, underwent 68 Ga- DOTATATE PET-CT, which showed a somatostatin receptor-expressing lesion in the left arch of foramen magnum that was correlated on MRI as a soft tissue lesion measuring 2.2 × 1.3 cm.
View Article and Find Full Text PDFClin Nucl Med
December 2024
From the Department of Radiology, University of California Davis, Sacramento, CA.
Accidental intra-arterial injections of radiotracers are rare events resulting in a specific imaging pattern, described as "hot-forearm," "hot-hand," "glove-phenomenon," or "glove-like pattern." We present a case 68 Ga-DOTATATE total-body PET/CT for restaging of a neuroendocrine tumor, where intra-arterial misinjection resulted in a glove phenomenon. Since patients may present with minimal symptoms, like in this case, and PET findings may only be seen at the distal upper extremity (placed above the head), these accidental injections may be more frequently detected with total-body PET/CT due to the longer field-of-view.
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