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The role of nailfold video-capillaroscopy in the assessment of dermatomyositis.
Rheumatology (Oxford)
December 2024
Department of Rheumatology, Affiliated Hospital of Nantong University, 20 Xisi Road, Jiangsu Province, Nantong, 226001, China.
Objectives: The clinical manifestations of dermatomyositis (DM) are diverse, nailfold video-capillaroscopy (NVC) can reflect microangiopathy, a process believed to contribute significantly to the clinical manifestations of DM. We aimed to explore the distinctive alterations and implications of nailfold capillary for evaluating disease progression in individuals with DM.
Methods: We gathered clinical data from 76 DM patients who underwent NVC in the Affiliated Hospital of Nantong University between September 2017 and September 2022.
Nailfold Video-Capillaroscopy in Sarcoidosis: New Perspectives and Challenges.
Tomography
September 2024
Pulmonology Unit, Department of Medical Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Introduction: Nailfold video-capillaroscopy (NVC) is a non-invasive cost-effective technique involving the microscopic examination of small blood vessels of the distal nailfold with a magnification device. It provides valuable information regarding the microcirculation including anomalies such as tortuous or dilated capillaries, hemorrhages, and avascular areas, which can characterize connective tissue diseases. The utility of NVC in the diagnosis and monitoring of systemic sclerosis (SSc) has been investigated in numerous studies allowing the distinction of the specific microvascular pattern of scleroderma from different conditions other than scleroderma (non-scleroderma pattern).
View Article and Find Full Text PDFNon-invasive Estimation of Microvasculopathy & Endothelial Dysfunction in Stem Cell Transplant Recipients and its Relationship with GVHD.
Blood Cell Ther
August 2024
Department of Clinical Hematology and Medical Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Introduction: Microvasculopathy and endothelial dysfunction play important roles in the development of post-transplant complications, including graft-versus-host disease (GVHD). We assessed structural microvasculopathy by employing nailfold video capillaroscopy (NFVC) and endothelial dysfunction via flow-mediated dilatation (FMD) of the brachial artery in recipients of hematopoietic stem cell transplantation.
Patients And Methods: Recipients of stem cell transplantation were included in this study post day+100 and divided into two cohorts.
A Comparison of Nailfold Video Capillaroscopy Findings in Mixed Connective Tissue Disease Interstitial Lung Disease vs Systemic Sclerosis Interstitial Lung Disease: A Single-Centre Study.
Mediterr J Rheumatol
June 2024
Department of Pulmonary Medicine, Kalinga Institute of Medical Sciences, KIIT University, Bhubaneswar, Odisha, India.
Article Synopsis
- The study aimed to compare nailfold capillaroscopy (NFC) findings and lung function between patients with Mixed Connective Tissue Disease associated Interstitial Lung Disease (MCTD-ILD) and those with Systemic Sclerosis associated Interstitial Lung Disease (SSc-ILD).
- The results indicated that significant capillaroscopic changes were more common in SSc-ILD patients (92%) compared to MCTD-ILD patients (72.3%), with SSc-ILD patients also showing greater lung function restrictions.
- The findings suggest that NFC can effectively identify lung damage severity, as more severe capillary abnormalities correlate with worse lung function in these conditions.
Audiovestibular Involvement in Patients With Systemic Sclerosis.
J Clin Rheumatol
October 2024
Otolaryngology Department, Centro Hospitalar do Baixo Vouga, Aveiro.
Introduction: Audiovestibular dysfunction has been reported in many autoimmune connective tissue diseases, including systemic sclerosis (SSc).
Objective: To assess the prevalence and features of audiological and vestibular disturbances in SSc patients and evaluate their relationship with disease duration, clinical features, nailfold videocapillaroscopy pattern, and immunologic profiles.
Method: A matched case-control study was conducted in a rheumatology clinic of a second-level hospital over 24 months.
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