Objective: To analyse the genotoxic risk of cytostatic drugs in health professionals after occupational exposure.
Method: The literature was searched using the databases PubMed, Lilacs, The Cochrane Library and Scopus with free and controlled language (MeSH terms) using Boolean operators AND and OR. The research was limited to articles published between 2005-2016.
Results: 11 articles were selected depending on their relevancy to this review's aim. Nine of the 11 articles proved the existence of damage to genetic material (DNA) of health workers, who were exposed to cytostatics. Furthermore, current security practices do not fully eliminate the chance of exposure. Therefore, new clinical trials are required.
Conclusions: Handling cytostatic drugs can cause a genotoxic risk to health workers who are exposed to these substances. This exposure may cause damage to the workers' DNA. There are not enough data to prove a cause-effect relationship between the genotoxic risk and adverse reactions in individuals. Health education will be the main way to raise awareness of and prevent this problem.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.enfcli.2019.07.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Children's palliative care perceptions and educational needs among healthcare professionals in humanitarian settings.
Palliat Support Care
January 2025
Department of Pediatrics, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Objectives: Explore humanitarian healthcare professionals' (HCPs) perceptions about implementing children's palliative care and to identify their educational needs and challenges, including learning topics, training methods, and barriers to education.
Methods: Humanitarian HCPs were interviewed about perspectives on children's palliative care and preferences and needs for training. Interviews were transcribed, coded, and arranged into overarching themes.
What are family caregivers' experiences of coordinating end-of-life care at home? A narrative review.
Palliat Support Care
January 2025
School of Nursing and Midwifery, University of Plymouth, Plymouth, UK.
Objectives: People with life-limiting diseases, who are no longer receiving active or curable treatment, often state their preferred place of care and death as the home. This requires coordinating a multidisciplinary approach, using available health and social care services to synchronize care. Family caregivers are key to enabling home-based end-of-life support; however, the 2 elements that facilitate success - coordination and family caregiver - are not necessarily associated as being intertwined or one and the same.
View Article and Find Full Text PDFWhile telegenetic counseling has increased substantially since the start of the COVID-19 pandemic, previous studies reported concerns around building rapport, nonverbal communication, and the patient-counselor relationship. This qualitative evaluation elicited feedback from genetic counselors, referring clinicians, and patients from a single healthcare organization to understand the user-driven reasons for overall satisfaction and experience. We conducted 22 in-depth, semi-structured interviews with participants from all 3 groups between February 2022 and February 2023.
View Article and Find Full Text PDFOccupational therapists' experiences of hegemony in a mental health setting: A practice-based enquiry.
Scand J Occup Ther
January 2025
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Background: Despite valuing occupation, occupational therapists report barriers to enacting occupation-based practice. One barrier noted in the literature is hegemony, the dominance of one social group's ideas over others. Specifically, biomedical and business models dominating healthcare are reported to significantly impact occupational therapists.
View Article and Find Full Text PDFPlaying a serious game to increase fertility awareness: perceptions of adolescents, parents and teachers.
Hum Fertil (Camb)
December 2025
Instituto Superior Miguel Torga, Coimbra, Portugal.
Infertility is increasing globally, affecting one in six adults due to factors like delayed childbearing and lifestyle changes. Despite the recognition of the importance of increasing fertility awareness, levels remain low. This study evaluated the perceptions of 'FActs!', a serious game aimed at improving adolescents' fertility awareness.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!