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Clinical presentation and outcomes of syphilitic meningitis among hospitalized adults in lusaka, Zambia.
Int J STD AIDS
October 2022
Department of Internal Medicine, 217901University of Zambia School of Medicine, Lusaka, Zambia.
Background: Few studies exist to describe the characteristics of symptomatic syphilitic meningitis, particularly in sub-Saharan Africa, despite a global resurgence.
Methods: We conducted a retrospective analysis of a cohort of adults with meningitis presenting to Zambia's largest referral hospital between April 2014 and December 2017. Individuals with pyogenic bacterial and cryptococcal meningitis were excluded from this cohort.
Spinal Syphilitic Gumma: A Rare Presentation of an Old Disease.
Case Rep Infect Dis
June 2021
Clinical Infection Unit, St. George's Hospital, BlackshawRoad, Tooting, London SW17 0QT, UK.
Syphilis is an ancient condition which still is of global concern today. Despite better awareness amongst clinicians and improving diagnostics, it remains likely underdiagnosed in part because of its namesake the 'great imitator.' While many patients suffer primary or secondary disease, tertiary syphilis characterised by gumma is rare, especially in the context of neurosyphilis.
View Article and Find Full Text PDFImmune reconstitution inflammatory syndrome associated with secondary syphilis.
Int J STD AIDS
March 2017
2 Division of Infectious Disease, Department of Internal Medicine, Wyckoff Heights Medical Center, Brooklyn, NY USA.
Immune reconstitution inflammatory syndrome (IRIS) is a condition associated with paradoxical worsening and/or new onset of an opportunistic infection in HIV patients following the initiation of anti-retroviral therapy or switching to more potent antiretroviral therapy (ART) regimen. Although IRIS associated with many opportunistic infections (OIs) has been well reported, syphilis has very rarely been mentioned in this regard. A 52-year-old male, diagnosed with AIDS six weeks ago, presented with the disseminated non-pruritic painless skin rash.
View Article and Find Full Text PDF[Inflammatory reconstitution immune syndrome associated to antiretroviral therapy and meningeal cryptococcosis].
Rev Med Chil
October 2006
Servicio de Neurología, Hospital Barros Luco-Trudeau.
The objective of high activity antiretroviral therapy (HAART) in patients with AIDS, is to obtain immune restoration. This means a reduction of the viral load and restitution of the CD4 cell count. A decreased rate of HIV replication improves both the number and function of CD4 cells.
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