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A Practical Clinical Approach to Navigate Pulmonary Embolism Management: A Primer and Narrative Review of the Evolving Landscape.
J Clin Med
December 2024
Section of Cardiology, Cardiology Division, NYU Langone Health and NYU School of Medicine, 550 First Avenue, New York, NY 10016, USA.
Advances in imaging, pharmacological, and procedural technologies have rapidly expanded the care of pulmonary embolism. Earlier, more accurate identification and quantification has enhanced risk stratification across the spectrum of the disease process, with a number of clinical tools available to prognosticate outcomes and guide treatment. Direct oral anticoagulants have enabled a consistent and more convenient long-term therapeutic option, with a greater shift toward outpatient treatment for a select group of low-risk patients.
View Article and Find Full Text PDFManagement of severe acute respiratory distress syndrome: a primer.
Crit Care
July 2023
Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO, 63110, USA.
This narrative review explores the physiology and evidence-based management of patients with severe acute respiratory distress syndrome (ARDS) and refractory hypoxemia, with a focus on mechanical ventilation, adjunctive therapies, and veno-venous extracorporeal membrane oxygenation (V-V ECMO). Severe ARDS cases increased dramatically worldwide during the Covid-19 pandemic and carry a high mortality. The mainstay of treatment to improve survival and ventilator-free days is proning, conservative fluid management, and lung protective ventilation.
View Article and Find Full Text PDFExtracorporeal cardiopulmonary resuscitation: A primer for pharmacists.
Am J Health Syst Pharm
July 2023
Department of Pharmacy and Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA.
Purpose: To describe the use of mechanical circulatory support in the setting of cardiac arrest and summarize pharmacists' role in extracorporeal cardiopulmonary resuscitation (ECPR).
Summary: ECPR is increasingly used to reduce morbidity and improve mortality after cardiac arrest. ECPR employs venoarterial ECMO, which provides full circulatory perfusion and gas exchange in both adult and pediatric patients in cardiac arrest.
Mechanical assist devices: A primer for the general anesthesiologist I: Extracorporeal membrane oxygenation.
J Clin Anesth
February 2023
Division of Cardiothoracic Anesthesiology, Department of Anesthesiology, Emory University, 1364 Clifton Rd. Suite C220, Atlanta, GA 30322, USA. Electronic address:
Mechanical Circulatory Support: Primer for Consultant Specialists.
Clin J Am Soc Nephrol
June 2022
Department of Anesthesiology, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York.
Mechanical life support therapies exist in many forms to temporarily replace the function of vital organs. Generally speaking, these tools are supportive therapy to allow for organ recovery but, at times, require transition to long-term mechanical support. This review will examine nonrenal extracorporeal life support for cardiac and pulmonary support as well as other mechanical circulatory support options.
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