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Scleredema in the Setting of Monoclonal Gammopathy of Unknown Significance With Progression to Multiple Myeloma: A Case Report.
Cureus
September 2023
Rheumatology, Mayo Clinic, Rochester, USA.
Type 2 scleredema on the background of monoclonal gammopathy of undetermined significance (MGUS) is a rare and progressive connective tissue disorder with very few cases reported to date. It is characterized by chronic and diffuse induration of the skin that begins in the upper back and neck and progresses proximally to distally, involving the shoulders, trunk, and arms; the hands are usually spared. Here, we present an unusual case of long-standing scleredema that progressed to involve the hands and fingers.
View Article and Find Full Text PDFNovel cutaneous eruptions in the setting of programmed cell death protein 1 inhibitor therapy.
JAAD Case Rep
January 2023
Department of Dermatology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Diabetes-associated dermatological manifestations in primary care and their association with vascular complications.
J Diabetes Metab Disord
December 2020
General Practice, 66650 Banuyls-sur-Mer, France.
Introduction: Although type 2 diabetes mellitus (DM) is a global public health problem, the diabetes-associated dermatological (non-infectious) manifestations (DADM) remain poorly understood and under-diagnosed. We aimed to evaluate the prevalence of 7 known DADM in a primary care setting, and their association macro/microvascular complications.
Methods: Cross-sectionnal study included patients consulting in general practice for DM-follow up, from November 2016 to January 2017.
Scleredema in the setting of Rheumatoid Arthritis.
Australas J Dermatol
February 2020
Department of Dermatology, Waikato Hospital, Hamilton, New Zealand.
New insights on scleromyxedema.
J Scleroderma Relat Disord
June 2019
Dermatology Clinic, Department Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Scleromyxedema is a rare fibromucinous disorders, with several clinical and pathological overlaps with scleroderma and scleredema. Etiopathogenesis remains uncovered, and no explanation has been provided either for the origin of mucin deposition or for the paraprotein role. The disease does not show gender predilection and affects mainly middle-age adults.
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