Hyperparathyroidism during pregnancy. Is it a diagnostic and therapeutic challenge?

Background: Primary hyperparathyroidism (PHPT) is characterized by an increase in parathyroid hormone (PTH) and hypercalcemia, which, when present during pregnancy, increases both maternal and fetal morbidity and mortality.

Objective: Emphasize the importance of surgical intervention in primary hyperparathyroidism during pregnancy.

Clinical Case: A 27-year-old female with a pregnancy of 27.2 weeks of gestation, with a diagnosis of symptomatic primary hyperparathyroidism secondary to parathyroid adenoma, a history of nephrolithiasis and severe acute pancreatitis, surgery was decided upon finding intrathyroid right parathyroid adenoma, post-surgical course with adequate evolution and remission of hyperparathyroidism.

Conclusions: Parathyroidectomy in primary hyperparathyroidism during pregnancy is safe.