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Triple Therapy (LABA-LAMA-Inhaled Corticosteroid) for COPD.
Am Fam Physician
January 2025
Department of Family Medicine, Medical University of South Carolina, Charleston.
Cannabis vaping elicits transcriptomic and metabolomic changes in inflammatory, oxidative stress and cancer pathways in human bronchial epithelial cells.
Am J Physiol Lung Cell Mol Physiol
January 2025
Research Institute of the, McGill University Health Centre, Montreal, QC, Canada.
The increasing shift from cannabis smoking to cannabis vaping is largely driven by the perception that vaping to form an aerosol represents a safer alternative to smoking and is a form of consumption appealing to youth. Herein, we compared the chemical composition and receptor-mediated activity of cannabis smoke extract (CaSE) to cannabis vaping extract (CaVE) along with the biological response in human bronchial epithelial cells. Chemical analysis using HPLC and GC/MS revealed that cannabis vaping aerosol contained fewer toxicants than smoke; CaSE and CaVE contained teratogens, carcinogens, and respiratory toxicants.
View Article and Find Full Text PDFAnesthetics change the oral microbial composition of children and increase the abundance of the genus .
Transl Pediatr
December 2024
Central Laboratory, Jiangxi Provincial Children's Hospital, The Affiliated Children's Hospital of Nanchang Medical College, Nanchang, China.
Background: Oral microbiome homeostasis is important for children's health, and microbial community is affected by anesthetics. The application of anesthetics in children's oral therapy has become a relatively mature method. This study aims to investigate the effect of different anesthesia techniques on children's oral microbiota.
View Article and Find Full Text PDFQuantitative Assessment of Postural Influence on Lung Function Using Deformable Image Registration-Based Breath-Hold CT Ventilation Imaging.
Cureus
December 2024
Department of Radiological Technology, Fujieda Municipal General Hospital, Fujieda, JPN.
Purpose This study aimed to clarify which positions are beneficial for patients with pathological lung diseases, such as acute respiratory distress syndrome, by obtaining lung ventilation and deformable vector field (DVF) images using Deformable Image Registration (DIR). Methods Thirteen healthy volunteers (5 female, 8 male) provided informed consent to participate to observe changes in normal lungs. DIR imaging was processed using the B-spline algorithm to obtain BH-CTVI (inhale, exhale) in four body positions (supine, prone, right lateral, left lateral) using DIR-based breath-hold CT ventilation imaging (BH-CTVI).
View Article and Find Full Text PDFA comparison of the treatment outcomes of cerebral gas embolism at 2.8 ATA in comparison with 6 ATA.
Undersea Hyperb Med
January 2025
Department of Hyperbaric Oxygen, Changhai Hospital, Naval Medical University, 168 Changhai Rd, Shanghai, 200433, China.
Objective: To investigate the effect of 6 ATA air/ oxygen treatment scheme and 2.8 ATA oxygen inhalation scheme on cerebral gas embolism.
Methods: 29 patients with cerebral gas embolism admitted from January 2014 to June 2022 were retrospectively included.
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