Objective: The objective of the study was to determine the optimal formula to estimate QT interval adjusting for QRS prolongation during right ventricular (RV) pacing.
Methods: This observational study included individuals (n = 43) with a newly implanted permanent ventricular pacemaker, who had a narrow QRS complex before pacemaker insertion. QT interval with RV pacing was related to QT interval before pacemaker implantation. The validation cohort (n = 442) had permanent RV pacing in DDD mode.
Results: A new QTc formula was derived utilizing the constants from the relationship between the spline heart rate QT correction (QTcRBK) before and after pacing; specifically, QTcRBK = QTcRBK × 0.86. The JT interval from paced complexes was highly heart rate (HR) dependent and was not accurate for QT assessment. Previous, QTc formula for paced complexes were not highly correlated with QT before pacing unless a robust HR correction is added. Formulae subtracting a fixed amount from QTc markedly overestimated QTc before pacing.
Conclusion: We proposed a new, simple formula for QT estimation in RV pacing. JT interval in paced complexes is highly HR dependent and is not accurate for QT assessment. The new spline approach for HR correction for the QT, once incorporated into some previously proposed formulae, blunts HR dependency and improves prediction of QT before pacing. QTcRBK*0.86 and QTcRBK - (QRS*0.5) demonstrated the best balance of relatively strong correlation to QTc before pacing and accurate QTc prolongation identification. Abnormal QT for QTcRBK*0.86 as defined by the 97.5th and 99th percentile are 469 and 479 ms respectively.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jelectrocard.2019.05.017 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
First Reports of Dual-Chamber Leadless Pacemaker Implantation via Intrajugular Access.
J Cardiovasc Electrophysiol
January 2025
Department of Cardiology, Heart Rhythm Specialists, McKinney, Texas, USA.
Introduction: The Aveir Dual-Chamber (DR) is the first entirely intracardiac dual-chamber leadless pacing system. Implantation of this device is typically achieved via femoral access, which may be a significant obstacle in patients with complex femoral vasculature or contraindications to femoral access.
Methods And Results: This report describes the world's first three cases of dual-chamber leadless pacemaker implantation via the right internal jugular vein.
Arrhythmia-Induced Atrial Cardiomyopathy: Clinical Relevance and Role of Premature Extrasystole Coupling Interval.
JACC Clin Electrophysiol
January 2025
Department of Medicine and Research Center, Montreal Heart Institute and Université de Montréal, Montréal, Québec, Canada; Institute of Pharmacology, West German Heart and Vascular Center, University of Duisburg-Essen, Essen, Germany. Electronic address:
The multifunctionality of the brainstem breathing control circuit.
Curr Opin Neurobiol
January 2025
Department of Physiology, University of California-San Francisco, San Francisco, CA 94143, USA.
Subconscious breathing is generated by a network of brainstem nodes with varying purposes, like pacing breathing or patterning a certain breath phase. Decades of anatomy, pharmacology, and physiology studies have identified and characterized the system's fundamental properties that produce robust breathing, and we now have well-conceived computational models of breathing that are based on the detailed descriptions of neuronal connectivity, biophysical properties, and functions in breathing. In total, we have a considerable understanding of the brainstem breathing control circuit.
View Article and Find Full Text PDFResearch on the network structure and gender/age differences of psychological safety among urban residents: network analysis based on a large sample.
BMC Psychol
January 2025
School of Economics and Management, China University of Geosciences (Beijing), Beijing, China.
Background: Psychological safety as the key to mental health, not only affects individual happiness and quality of life but also relates to social stability and harmony. However, psychological safety is complex and multidimensional, with unclear internal structures and influencing factors and insufficient research on gender and age differences. Urban residents are living in an environment characterized by fast-paced, high-pressure, multicultural integration, and complex social relationships.
View Article and Find Full Text PDFLeadless Pacemaker Implantation Following Lead Extraction in a Patient With Recent Percutaneous Tricuspid Valve Repair.
Pacing Clin Electrophysiol
January 2025
Second Division of Cardiology, Cardiac-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
This case details the successful implantation of a leadless pacemaker following the extraction of transvenous leads in a 72-year-old female patient with a complex cardiovascular history. The patient had undergone a series of cardiac interventions, including a recent percutaneous tricuspid valve repair with a metal clip implant due to severe regurgitation. After presenting with an infection at the pacemaker site, methicillin-resistant Staphylococcus hominis was identified, necessitating the removal of the entire pacing system.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!