Pharyngeal dysfunction associated with early and late onset sleep disordered breathing in children.

Int J Pediatr Otorhinolaryngol

Pediatric Otolaryngology, Division of Pediatric Surgery & Division of Otolaryngology (Department of Surgery), The Stollery Children's Hospital & University of Alberta Hospitals, Edmonton, Alberta, Canada. Electronic address:

Published: December 2019

Objective: To compare the frequency and type of diagnoses associated with pharyngeal dysfunction (PD) in children presenting with early versus late onset sleep disordered breathing (SDB).

Methods: This was a retrospective, cross-sectional study. A consecutive series of children ≤3 years old who underwent management for SDB were retrospectively identified from a prospectively kept surgical database. The early onset group was compared with two separate late onset (≥4years old) groups. Diagnoses associated with PD included gastroesophageal reflux disease (GERD), swallowing dysfunction, prematurity, asthma, and obesity. Distribution of PD diagnoses, airway lesions, syndromic conditions, pulse oximetry scores, and endoscopic pattern of airway obstruction were compared.

Results: 73 patients with early onset SDB were identified (51 boys, mean age 2.25 ± 0.64 years, range 1.75-3 years) and compared with two groups of later onset SDB consisting of 75 and 72 patients with mean ages of 7.58 ± 2.40 years and 8.04 ± 3.34 years respectively (range 4-16 years). The early onset SDB group had a higher prevalence of PD diagnoses compared to the later onset group with 35 of 73 patients being diagnosed compared to 41 of 147 children (p = 0.01). Early onset SDB patients were more likely to have GERD or swallowing dysfunction (p < 0.01) while later onset patients more commonly presented with associated asthma or obesity (p < 0.01). There was no statistically significant difference in airway lesions between groups.

Conclusion: Early-onset SDB is associated with conditions causing PD more often than later-onset SDB. Identifying these conditions and optimizing their management may impact outcomes in treating pediatric SDB.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijporl.2019.109667DOI Listing

Publication Analysis

Top Keywords

early onset
16
onset sdb
16
late onset
12
onset
9
pharyngeal dysfunction
8
onset sleep
8
sleep disordered
8
disordered breathing
8
diagnoses associated
8
onset group
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!