AI Article Synopsis
- Ischemic and hemorrhagic strokes are serious conditions that result in high rates of death and disability, highlighting the need for new treatment strategies.* -
- Matricellular proteins are unique extracellular matrix proteins that play various roles in bodily functions, particularly in relation to stroke mechanisms.* -
- The article reviews research on the role of matricellular proteins in stroke and explores possible therapeutic applications for these proteins.*
Article Abstract
Both ischemic and hemorrhagic strokes are still serious diseases with high mortalities and morbidities. To improve outcomes of strokes, new therapeutic approaches need to be developed. Matricellular proteins are inducible, multifunctional and non-structural extracellular matrix proteins, which are definitely differentiated from classical ones due to the unusual diversity of functions. There are many matricellular proteins known, most of which may be involved in the pathophysiology and the protective or repairing mechanisms of strokes. This article reviews the available information regarding potential roles of matricellular proteins in stroke, and discusses the potential therapeutic approaches against stroke using matricellular proteins.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.expneurol.2019.113057 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!