AI Article Synopsis
- Cytomegalovirus (CMV) is the most common viral infection in organ transplant recipients, often affecting organs like the brain and lungs, but renal involvement is rare.
- This study presents six cases of biopsy-proven CMV renal infection, with five patients showing detectable CMV viremia.
- Four patients had improved kidney function after treatment, making this the largest case series of confirmed CMV renal infection from one center.
Article Abstract
Cytomegalovirus is the most common viral infection in organ transplant recipients that usually affects the brain, lungs, liver, and gastrointestinal tract. Renal involvement of Cytomegalovirus (CMV) is otherwise rare. We present six cases of biopsy-proven CMV renal infection. Five out of the six patients had detectable CMV viremia. Kidney biopsy revealed glomerulopathy in four cases and tubulointerstitial involvement in two cases. All patients exhibited decline in renal function at the onset of infection. Four out of six patients had improvement of renal function following treatment of CMV disease. To date, this is the largest case series of pure biopsy-proven CMV renal infection described in a single center.
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| http://dx.doi.org/10.1111/tid.13169 | DOI Listing |
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