Technological innovation has become an integral and inescapable aspect of our daily existence as almost everything of significance in our world now has a cyber (i.e., relating to, or involving computers, computer networks, information technology, and virtual reality) component associated with it. Every facet of our lives is now touched by technology. As such, we're experiencing a digital transformation. Unfortunately, both as individuals and as a society, we're inadequately prepared to embrace the myriad of vulnerabilities presented by cybertechnologies. Unintended cyber vulnerabilities present significant risks to individuals, organizations, governments and economies. Here, we identify current cybersecurity vulnerabilities found in the life science enterprise and discuss the many ways in which these vulnerabilities present risk to laboratory workers in these facilities, the surrounding community and the environment. We also consider the cyberbiosecurity benefits associated with numerous innovations likely to be present in the laboratory of the future. The challenges associated with cyberbiosecurity vulnerabilities are not insurmountable; they simply require thoughtful consideration by equipment designers, software and control systems developers, and by end users. Organizations and the individuals that comprise them must respect, value, and protect their data. End users must train themselves to look at every piece of laboratory equipment and every process from a cyberbiosecurity perspective. With this approach, cyberbiosecurity vulnerabilities can be minimized or eliminated to the benefit of workers, life science organizations, and national security.
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http://dx.doi.org/10.3389/fbioe.2019.00182 | DOI Listing |
J Agric Food Chem
January 2025
China-Kenya Joint Laboratory for Ecological Pest Control of Citrus, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Key Laboratory of Biopesticide and Chemical Biology, MOE, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
RNA pesticides have emerged as a promising alternative to conventional chemical pesticides due to their high specificity and minimal environmental impact. However, the instability of RNA molecules in the environment and the challenges associated with their effective delivery to target pests limit their broader application. This study addresses these challenges by developing a dual delivery system using chitosan (CS) and Metal-Organic Frameworks (MOFs) to enhance the delivery and efficacy of double-stranded RNA (dsRNA) and cycloxaprid against , a vector of citrus greening disease.
View Article and Find Full Text PDFRecent Adv Drug Deliv Formul
January 2025
Central Laboratory, Shenzhen Bao'an District Songgang People's Hospital, Shenzhen, China.
Exosomes are nanoscale extracellular vesicles with various biological activities that can accelerate wound healing by regulating inflammatory responses, promoting cell proliferation and angiogenesis, and other mechanisms. Among them, plant and animal exosomes have demonstrated unique advantages due to their biological characteristics. Plant exosomes have gradually become a research hotspot due to their wide source, high biosafety, and low production cost, demonstrating significant pro-healing potential.
View Article and Find Full Text PDFFront Oncol
January 2025
School of Laboratory Medicine, Chengdu Medical College, Chengdu, Sichuan, China.
Multiple Myeloma (MM) is the second most common malignancy of the hematopoietic system, accounting for approximately 10% of all hematological malignancies, and currently, there is no complete cure. Existing research indicates that exosomal long non-coding RNAs (lncRNAs) play a crucial regulatory role in the initiation and progression of tumors, involving various interactions such as lncRNA-miRNA, lncRNA-mRNA, and lncRNA-RNA binding proteins (RBP). Despite the significant clinical application potential of exosomal lncRNAs, research in this area still faces challenges due to their low abundance and technical limitations.
View Article and Find Full Text PDFJ Orthop Translat
January 2025
Department of Joint and Orthopedics, Orthopedic Center, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou, Guangdong, 51282, China.
Unlabelled: The treatment of orthopaedic diseases, such as fractures and osteoarthritis, remains a significant challenge due to the complex requirements for mechanical strength and tissue repair. Hydrogels based on hyaluronic acid methacrylate (HAMA) show promise as tissue engineering materials for these conditions. Hyaluronic acid (HA) is a natural component of the extracellular matrix, known for its good compatibility.
View Article and Find Full Text PDFACS Appl Energy Mater
January 2025
School of Advanced Materials Science and Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
Organic solar cells (OSCs) are attracting significant attention due to their low cost, lightweight, and flexible nature. The introduction of nonfullerene acceptors (NFAs) has propelled OSC development into a transformative era. However, the limited availability of wide band gap polymer donors for NFAs poses a critical challenge, hindering further advancements.
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