Aging of the Hematopoietic Stem Cell Niche: An Unnerving Matter.

Cell Stem Cell

Erasmus Medical Center Cancer Institute, Department of Hematology, Faculty Building Rm Ee-1393. dr. Molewaterplein 50, 3015GE Rotterdam, the Netherlands. Electronic address:

Published: September 2019

The drivers of aging in the hematopoietic system remain incompletely understood. In this issue of Cell Stem Cell, Ho et al. (2019) report that functional switching of β-adrenergic nerve signaling underlies remodeling of stem cell niches, driving age-associated alterations in hematopoiesis.

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http://dx.doi.org/10.1016/j.stem.2019.08.008DOI Listing

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