Nucleic acid-based theranostics in type 1 diabetes.

Transl Res

Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, Michigan. Electronic address:

Published: December 2019

AI Article Synopsis

  • RNA interference (RNAi) offers a promising approach for treating type 1 diabetes (T1D) by targeting specific genes for therapy.
  • The review will cover methods for delivering oligonucleotides and the imaging techniques used to track their delivery.
  • It will also explore potential therapeutic targets and various combined diagnostic and therapeutic strategies (theranostics) for managing T1D.

Article Abstract

Application of RNAi interference for type 1 diabetes (T1D) therapy bears tremendous potential. This review will discuss vehicles for oligonucleotide delivery, imaging modalities used for delivery monitoring, therapeutic targets, and different theranostic strategies that can be applied for T1D treatment.

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Source
http://dx.doi.org/10.1016/j.trsl.2019.08.006DOI Listing

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