We consider an out-of-equilibrium lattice model consisting of 2D discrete rotators, in contact with heat reservoirs at different temperatures. The equilibrium counterpart of such a model, the clock model, exhibits three phases: a low-temperature ordered phase, a quasiliquid phase, and a high-temperature disordered phase, with two corresponding phase transitions. In the out-of-equilibrium model the simultaneous breaking of spatial symmetry and thermal equilibrium gives rise to directed rotation of the spin variables. In this regime the system behaves as a thermal machine converting heat currents into motion. In order to quantify the susceptibility of the machine to the thermodynamic force driving it out of equilibrium, we introduce and study a dynamical response function. We show that the optimal operational regime for such a thermal machine occurs when the out-of-equilibrium disturbance is applied around the critical temperature at the boundary between the first two phases, namely, where the system is mostly susceptible to external thermodynamic forces and exhibits a sharper transition. We thus argue that critical fluctuations in a system of interacting motors can be exploited to enhance the machine overall dynamic and thermodynamic performances.
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http://dx.doi.org/10.1103/PhysRevLett.123.070601 | DOI Listing |
Sensors (Basel)
December 2024
School of Information and Electronic Engineering, Zhejiang University of Science and Technology, Liuxia Street, Hangzhou 310023, China.
Broadcast ephemeris data are essential for the precision and reliability of the BeiDou Navigation Satellite System (BDS) but are highly susceptible to anomalies caused by various interference factors, such as ionospheric and tropospheric effects, solar radiation pressure, and satellite clock biases. Traditional threshold-based methods and manual review processes are often insufficient for detecting these complex anomalies, especially considering the distinct characteristics of different satellite types. To address these limitations, this study proposes an automated anomaly detection method using the IF-TEA-LSTM model.
View Article and Find Full Text PDFMicroorganisms
December 2024
Operative Research Unit of Laboratory, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128 Rome, Italy.
Multidrug-resistant is a significant healthcare challenge that particularly affects vulnerable patients through opportunistic nosocomial infections. Surveillance is crucial for monitoring the prevalence of these infections. Eighty-four KPC strains (2019-2022) were collected from patients admitted in Fondazione Policlinico Universitario Campus Bio-Medico.
View Article and Find Full Text PDFJ Clin Med
December 2024
Scientific Institute IRCCS "E. Medea", Scientific Direction, 23842 Bosisio Parini, Italy.
: Chronobiology has gained attention in the context of paediatric neurological and neuropsychiatric disorders, including migraine, epilepsy, autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and post-traumatic stress disorder (PTSD). Disruptions in circadian rhythms are associated with key symptoms such as sleep disturbances, mood dysregulation, and cognitive impairments, suggesting a potential for chronobiology-based therapeutic approaches. : This narrative review employs a systematic approach to identify relevant studies through searches of three major scientific databases, NCBI/PubMed, ScienceDirect, and Scopus, up to July 2024.
View Article and Find Full Text PDFBioengineering (Basel)
November 2024
State Key Laboratory of Bioactive Molecules and Drug Gability Assessment, Jinan University, No. 855 East Xingye Avenue, Guangzhou 510632, China.
While TGF-β3 promoted defect healing in a primate baboon skull defect model and patients, it remains unclear whether TGF-β3 affects the formation of osteoclasts and bone resorption between osteogenesis and osteolysis. Analysis of the full transcriptome of hPDLSCs (human periodontal ligament stem cells) revealed that the expression of RANKL was significantly up-regulated after TGF-β3 treatment during osteogenesis, which suggests its involvement in clock-controlled autophagy in bone metabolism. TRAP staining and bone resorption lacunae were used to assess the osteoclasts formed from RANKL-induced differentiated BMMs.
View Article and Find Full Text PDFGenes (Basel)
November 2024
Laboratory of Genetics of Aging and Longevity, Kazan State Medical University, 420012 Kazan, Russia.
Background: Obesity is a global health issue influenced primarily by genetic variants and environmental factors. This study aimed to examine the relationship between genetic and lifestyle factors and their interaction with obesity risk among university students.
Methods: A total of 658 students from the same university participated in this study, including 531 females (mean age (SD): 21.
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