Paraquat is one of the most commonly used lethal herbicide. Even the small amount of paraquat is hazardous to human beings. Poisoning by paraquat is most commonly happening in agricultural based economical country. This poison is a threat to public health and its high mortality rate is responsible for a significant number of death. We hereby report a case of 38-year-old male with a history of accidental paraquat ingestion. He works as a gardener which contributes to the ease in availability of the poison. He had the post accidental paraquat consumption complaints of lip sores, swallowing difficulty and hypersalivation in more amount. The patient was admitted in the Casualty and underwent the supportive treatment. Laboratory investigations were found to be normal except WBC count which was elevated. Early diagnosis and proper management can reduce the mortality rate and even small amount of paraquat can lead to some major fatal outcomes. At present there is no specific antidote available so there is a need to focus more on the prevention and management of paraquat poisoning.
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http://dx.doi.org/10.1007/s40199-019-00298-9 | DOI Listing |
Zhonghua Liu Xing Bing Xue Za Zhi
October 2024
Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Indian J Crit Care Med
August 2024
Department of Critical Care Medicine, Dayanand Medical College & Hospital, Ludhiana, Punjab, India.
Introduction: Accidental or intentional ingestion of paraquat leads to many local and systemic effects and the mortality rate is very high. There is limited data from North India and our objectives were to study the spectrum of presentation, treatment given, and its relation with outcome in a tertiary care setting.
Materials And Methods: This retrospective observational study was conducted after ethical approval and data regarding demography, clinical features, duration of presentation, organ involvement, renal replacement therapy (RRT), management, and outcome was collected.
MethodsX
June 2024
Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 9177948564, Iran.
This paper provides a complete protocol for studying the effects of inhaled paraquat (PQ), a toxic herbicide that has negative effects systemically and on the lungs. The protocol aims to evaluate the effects of aerosolized PQ exposure on lung and systemic injury in an animal model, which will provide significant information for therapeutic interventions for PQ-induced pulmonary and systemic damage. The protocol involves the following key components: 1.
View Article and Find Full Text PDFJ Assoc Physicians India
March 2024
Consultant, IVY Hospital, Mohali, Punjab, India.
Paraquat (1,1'-dimethyl-4,4'-dipyridylium) is a liquid herbicide, linked to both accidental and intentional ingestion, which can result in severe and frequently lethal poisoning. It has been known to cause injury to the lungs, kidneys, and liver. We retrospectively reviewed five cases over the last 4 years with a history of paraquat ingestion.
View Article and Find Full Text PDFToxicol Rep
December 2023
Department of Medicine, Sylhet MAG Osmani Medical College, Sylhet 3100, Bangladesh.
Background: Paraquat poisoning is one of the leading causes of fatal poisoning in many parts of the world, especially in agricultural countries. Its high toxicity even in small amounts causes rapid damage to multiple organs, especially the kidneys, lungs, and liver, mainly through free radical-mediated injury. As no specific antidote is yet available, early diagnosis and the importance of supportive therapy are critical parts of management.
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