Monte Carlo simulations, MCNP5 and Geant4 codes were developed to investigate radiation shielding properties of xPbO-(50-x) BaO-50B2O3 (where 5 ≤ x ≤ 45 mol%) consider to be glass systems. The mass attenuation coefficients were evaluated for different PbO concentration in the glass samples for varies photon energies of 0.356, 0.662, 1.173 and 1.332 MeV. The obtained mass attenuation coefficient values used to calculate half-value layer, effective atomic number, and electron density. The simulation parameters were compared with experimental data. Results show that the simulation results of mass attenuation coefficients for all PbO concentrations were generally in good agreement with experimental results, however, mass attenuation coefficient values calculated using Geant4 were slightly lower than MCNP5 and experimental data on the low energy of 0.356 MeV. The results obtained from MCNP5 and Geant4 codes might be able to assessment mass attenuation for different glass systems. Furthermore, gamma ray, fast neutron and charged particle interaction for the glass systems were studied using buildup factors, fast neutron removal cross sections and ranges respectively.
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http://dx.doi.org/10.1016/j.heliyon.2019.e02364 | DOI Listing |
Sci Rep
December 2024
Department of Gastroenterology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Jiangxi, 330006, China.
Adipose tissue-derived adipokines facilitate inter-organ communication between adipose tissue and other organs. Omentin-1, an adipokine, has been implicated in the regulation of glucose and insulin metabolism. However, limited knowledge exists regarding the regulatory impact of endogenous omentin-1 on hepatic steatosis.
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December 2024
Department of Orthopaedic Surgery, Keck School of Medicine, Stem Cell Research and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA.
Interleukin-6 (IL-6) is a major pro-inflammatory cytokine that demonstrates a robust correlation with age and body mass index (BMI) as part of the senescence-associated secretory phenotype. IL-6 cytokines also play a crucial role in metabolic homeostasis and regenerative processes primarily via the canonical STAT3 pathway. Thus, selective modulation of IL-6 signaling may offer a unique opportunity for therapeutic interventions.
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December 2024
Institute of Physiology, iCBR, Faculty of Medicine, University of Coimbra, Subunit 1, polo 3, Azinhaga de Santa Comba, Celas, 3000-548, Coimbra, Portugal.
Perivascular adipose tissue (PVAT) is a dynamic tissue that affects vascular function and cardiovascular health. The connection between PVAT, the immune system, obesity, and vascular disease is complex and plays a pivotal role in the pathogenesis of vascular diseases such as atherosclerosis, hypertension, and vascular inflammation. In cardiometabolic diseases, PVAT becomes a significant source of proflammatory adipokines, leading to increased infiltration of immune cells, in cardiometabolic diseases, PVAT becomes a significant source of proinflammatory adipokines, leading to increased infiltration of immune cells, promoting vascular smooth muscle cell proliferation and migrationpromoting vascular smooth muscle cell proliferation and migration.
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December 2024
Department of Rehabilitation, School of Medical Technology, Tianjin Medical University, Tianjin 300070, China. Electronic address:
This study aimed to investigate the underlying mechanisms by which physical exercise mitigates muscle atrophy induced by Dexamethasone (Dex). A muscle atrophy model was established in the mouse C2C12 cell line and 8-week-old mice treated with Dex, with subsequent verification of phenotype and atrogene expression. The potential benefits of combined aerobic and resistance exercise in mitigating muscle atrophy were then examined.
View Article and Find Full Text PDFClin Nutr
December 2024
Faculty of Sport and Health Sciences, Gerontology Research Center, University of Jyväskylä, 40014 Jyväskylä, Finland; The Wellbeing Services County of Central Finland, 40620 Jyväskylä, Finland. Electronic address:
Background & Aims: Suboptimal diets increase morbidity and mortality risk. Epigenetic clocks are algorithms that can assess health and lifespan, even at a young age, before clinical manifestations of diseases. We investigated the association between dietary patterns and biological aging in young adult twins.
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