Sixteen New Prenylated Flavonoids from the Fruit of .

Molecules

Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine, Development of Henan Province, Henan University of Chinese Medicine, Zhengzhou 450046, China.

Published: September 2019

Sixteen new prenylated flavonoids, sinoflavonoids P-Z (-) and sinoflavonoids NA-NE (-), were isolated from the fruit of , along with eight known analogues (-). Their structures were elucidated on the basis of extensive spectroscopic data (HR-ESI-MS, H-NMR, C-NMR, HSQC, HMBC). The cytotoxic activities of compounds -, , and were evaluated by MTT assay. Compound showed the most potent cytotoxicity in MCF-7, and HepG2 cell lines, with IC values of 6.25 and 3.83 μM, respectively.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749350PMC
http://dx.doi.org/10.3390/molecules24173196DOI Listing

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