Purpose: The aim of this study was to investigate the diagnostic value of renal parenchymal density differences in distinguishing between acute and chronic urinary dilatations.
Material And Methods: Retrospectively, unenhanced CTs of 98 patients were evaluated. Thirty-three had acute urinary obstruction, and 33 had chronic urinary obstruction. Parenchymal density values (HU) and renal pelvic anterior-posterior (AP) diameters of all groups were evaluated by two different radiologists who were unaware of each other and the content of the study. The -test was used to compare parenchymal densities and renal pelvic diameter differences with normal, acute urinary dilation and chronic urinary dilation groups.
Results: Of the 98 cases who were included in the study, 33 people were in the acute obstruction group (7 females, 26 males), and 33 were in the chronic obstruction group. However, the second observer (observer 2) found a statistically significant difference ( < 0.01) during the measurements of density between the obstructed and normal sides. While for the first observer (observer 1), the correlation between right and left renal density measurements of the normal cases was moderate at 0.576; correlation of measurements done by the second observer was found to be high at 0.777.
Conclusions: Pale kidney findings seems to be helpful in diagnosis of acute urinary occlusion, but different results are obtained with evaluations made by different observers. Moreover, it is not a specific finding because oedema can also be seen in some other conditions, such as acute pyelonephritis; for this reason, one must be careful during the evaluation of this finding.
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http://dx.doi.org/10.5114/pjr.2019.86822 | DOI Listing |
Int J Endocrinol
January 2025
Nephrology Department, Jiangxi Provincial Key Research Laboratory of Traditional Chinese Medicine, Key Research Laboratory of Chronic Renal Failure, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006, China.
This study aimed to investigate the potential mechanisms of puerarin in alleviating diabetic nephropathy (DKD) in mice. The DKD model was induced by multiple low-dose injections of streptozotocin (STZ) and a high-sugar and high-fat diet in male C57BL/6J mice. After confirming the onset of DKD, mice were given irbesartan, distilled water, or different concentrations of puerarin (40 and 80 mg/kg/d) by gavage for 8 weeks.
View Article and Find Full Text PDFBiomed Rep
March 2025
Department of Rheumatology and Immunology, People's Hospital of Longhua, Shenzhen, Guangdong 518109, P.R. China.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex etiology primarily linked to abnormalities in B lymphocytes within the human body, resulting in the production of numerous pathogenic autoantibodies. Telitacicept is a relatively novel humanized, recombinant transmembrane activator, calcium modulator and cyclophilin ligand interactor fused with the Fc portion (TACI-Fc). It works by competitively inhibiting the TACI site, neutralizing the activity of B-cell lymphocyte stimulator and A proliferation-inducing ligand.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Objective: The C-reactive protein/Lymphocyte Ratio (CLR) is a novel biomarker whose role in the development of chronic kidney disease (CKD) is not well understood. This study aimed to investigate the correlation between CLR and the prevalence of CKD.
Methods: This cross-sectional study included participants from the US National Health and Nutrition Examination Survey conducted between 1999 and 2010.
J Anus Rectum Colon
January 2025
Department of Infectious Diseases, St. Marianna University School of Medicine, Kawasaki, Japan.
Fever and diarrhea are the common symptoms of infection (CDI); however, pseudomembranous enteritis, megacolonization, and paralytic ileus have been observed in severe cases. spores are resistant to several types of disinfectants. Thus, they are often the causative pathogens of healthcare-associated infections.
View Article and Find Full Text PDFFront Public Health
January 2025
School of Nursing, Jinzhou Medical University, Jinzhou, China.
Background: With the global trend of aging, stress urinary incontinence is becoming more common in older adults, which may have some impact on patients' quality of life. Social alienation can generate negative emotions such as anxiety, depression, loneliness, and morbid stigma, and reduce patients' quality of life. However, the current status of social alienation is different among different older adult female patients with stress urinary incontinence.
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