Defensive burying of flavors paired with lithium but not amphetamine.

Psychopharmacology (Berl)

Division of Psychology and Philosophy, Sam Houston State University, Huntville, TX 77341.

Published: April 1989

Although rats demonstrated avoidance of both lithium- and amphetamine-paired flavored solutions, only the lithium-paired flavor elicited a defensive burying response. These data support the contention that lithium-paired flavors become hedonically unpalatable. Additionally, a simplified economical method for measuring defensive burying is described.

Download full-text PDF

Source
http://dx.doi.org/10.1007/BF00177569DOI Listing

Publication Analysis

Top Keywords

defensive burying
12
burying flavors
4
flavors paired
4
paired lithium
4
lithium amphetamine
4
amphetamine rats
4
rats demonstrated
4
demonstrated avoidance
4
avoidance lithium-
4
lithium- amphetamine-paired
4

Similar Publications

Robert Wartenberg and the Hallervorden Affair, 1953: A Clash Between Medical Ethics and Cold War Politics.

Neurology

January 2025

Department of Neurology, Henry Ford Health, Detroit, MI; and.

Robert Wartenberg was an emigrant from Nazi Germany and an iconic pioneer in neurology, describing eponyms and helping to found and nurture the American Academy of Neurology. However, in 1953, ironically, he became embroiled in a controversial event regarding the German neuroscientist and Nazi collaborator Julius Hallervorden. Wartenberg attempted to convince the Dutch delegation to attend the International Neurological Congress in Lisbon from which they had withdrawn in response to Hallervorden's inclusion as a speaker.

View Article and Find Full Text PDF

The translational value of the marble burying task (MBT) is debatable. Here we performed video analysis of behaviors during the MBT to accurately capture the details of all behaviors displayed during this task. Our results show that a count of marbles buried at the end of the task may not be a good translational correlate of the 'intentional marble burying' that the task is assumed to measure.

View Article and Find Full Text PDF

Pre-operative environmental enrichment does not yield a prophylactic effect against traumatic brain injury-induced neurobehavioral deficits.

Exp Neurol

January 2025

Department of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA; Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA; Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

Article Synopsis
  • Environmental enrichment (EE) effectively improves neurobehavioral and cognitive functions following traumatic brain injury (TBI), but its preventative effects against TBI are uncertain.
  • The study hypothesized that EE before TBI surgery would protect against deficits and suggest additional benefits if EE was provided both before and after the injury.
  • Results showed that while pre-injury EE didn't provide a protective effect against TBI, rats with post-injury EE performed better in motor skills and cognitive tests compared to those without enrichment.
View Article and Find Full Text PDF

Stress strongly influences the physiology and behavior of animals, and leads into a pathological condition and disease. NMDA receptors (NMDARs) play a crucial role in the modulation of neural activity. To understand the role of NMDARs in fish stress response, we used NMDARs agonist aspartate to test the functional role of its input on the Dahlgren cell population in the caudal neurosecretory system (CNSS) of the olive flounder.

View Article and Find Full Text PDF

The activation of autonomic and hypothalamo-pituitary-adrenal (HPA) systems occurs interdependently with behavioral adjustments under varying environmental demands. Nevertheless, laboratory rodent studies examining the neural bases of stress responses have generally attributed increments in these systems to be monolithic, regardless of whether an active or passive coping strategy is employed. Using the shock probe defensive burying test (SPDB) to measure stress-coping features naturalistically in male and female rats, we identify a neural pathway whereby activity changes may promote distinctive response patterns of hemodynamic and HPA indices typifying active and passive coping phenotypes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!