Although rats demonstrated avoidance of both lithium- and amphetamine-paired flavored solutions, only the lithium-paired flavor elicited a defensive burying response. These data support the contention that lithium-paired flavors become hedonically unpalatable. Additionally, a simplified economical method for measuring defensive burying is described.
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http://dx.doi.org/10.1007/BF00177569 | DOI Listing |
Neurology
January 2025
Department of Neurology, Henry Ford Health, Detroit, MI; and.
Robert Wartenberg was an emigrant from Nazi Germany and an iconic pioneer in neurology, describing eponyms and helping to found and nurture the American Academy of Neurology. However, in 1953, ironically, he became embroiled in a controversial event regarding the German neuroscientist and Nazi collaborator Julius Hallervorden. Wartenberg attempted to convince the Dutch delegation to attend the International Neurological Congress in Lisbon from which they had withdrawn in response to Hallervorden's inclusion as a speaker.
View Article and Find Full Text PDFLab Anim (NY)
December 2024
Department of Pediatrics, Harvard Medical School, Massachusetts General Hospital, Lurie Center for Autism, Charlestown, MA, USA.
The translational value of the marble burying task (MBT) is debatable. Here we performed video analysis of behaviors during the MBT to accurately capture the details of all behaviors displayed during this task. Our results show that a count of marbles buried at the end of the task may not be a good translational correlate of the 'intentional marble burying' that the task is assumed to measure.
View Article and Find Full Text PDFExp Neurol
January 2025
Department of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA; Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA; Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:
Stress strongly influences the physiology and behavior of animals, and leads into a pathological condition and disease. NMDA receptors (NMDARs) play a crucial role in the modulation of neural activity. To understand the role of NMDARs in fish stress response, we used NMDARs agonist aspartate to test the functional role of its input on the Dahlgren cell population in the caudal neurosecretory system (CNSS) of the olive flounder.
View Article and Find Full Text PDFJ Neurosci
November 2024
Interdisciplinary Neuroscience Program, University of Iowa, Iowa City, Iowa 52242
The activation of autonomic and hypothalamo-pituitary-adrenal (HPA) systems occurs interdependently with behavioral adjustments under varying environmental demands. Nevertheless, laboratory rodent studies examining the neural bases of stress responses have generally attributed increments in these systems to be monolithic, regardless of whether an active or passive coping strategy is employed. Using the shock probe defensive burying test (SPDB) to measure stress-coping features naturalistically in male and female rats, we identify a neural pathway whereby activity changes may promote distinctive response patterns of hemodynamic and HPA indices typifying active and passive coping phenotypes.
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