Long-Term Non-Invasive Ventilation for Chronic Respiratory Failure Non-invasive long-term ventilation (NIV) may be helpful for selected patients with severe COPD and chronic respiratory lailure (chronic hypercapnia and hypoxemia). The patient described in the case report became normocapnic under long-term NIV and both her sleep and quality of life improved significantly. She also suffered fewer COPD exacerbations and was better able to cope with them herself with the help of NIV.
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