Advances in instrumentation and computational analysis in proteomics have opened new doors for honeybee biological research at the molecular and biochemical levels. Proteomics has greatly expanded the understanding of honeybee biology since its introduction in 2005, through which key signaling pathways and proteins that drive honeybee development and behavioral physiology have been identified. This is critical for downstream mechanistic investigation by knocking a gene down/out or overexpressing it and being able to attribute a specific phenotype/biochemical change to that gene. Here, we review how emerging proteome research has contributed to the new understanding of honeybee biology. A systematic and comprehensive analysis of global scientific progress in honeybee proteome research is essential for a better understanding of research topics and trends, and is potentially useful for future research directions.
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http://dx.doi.org/10.3390/ijms20174252 | DOI Listing |
Sci Total Environ
January 2025
Université de Lorraine, INRAE, LSE, F-54000 Nancy, France.
Pesticides have a significant impact on the environment, harming valuable non-target organisms like bees. Honeybees, in particular, are ideal bioindicators of pesticide exposure due to extensive research on how pesticides affect their behavior, immunity, development, biomolecules, and detoxification. However, wild pollinators are less studied in terms of pesticide exposure, and their inclusion is essential for a comprehensive risk assessment.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Departamento de Biologia Geral, Universidade Federal de Viçosa, Viçosa, MG, Brazil. Electronic address:
Bee population decline is associated with various stressors, including exposure to pollutants. Among these, titanium dioxide (TiO), an emerging nanoparticle (NP) pollutant, potentially affects living organisms, including bees. This study evaluates the impact of TiO NPs ingestion (1.
View Article and Find Full Text PDFPathogens
January 2025
Biology Department, University of Massachusetts Boston, Boston, MA 02125, USA.
Bumblebees, the most important wild pollinators in both agricultural and natural ecosystems, are declining worldwide. The global decline of bumblebees may threaten biodiversity, pollination services, and, ultimately, agricultural productivity. Several factors, including pesticide usage, climate change, habitat loss, and species invasion, have been documented in the decline of bumblebee species, but recent studies have revealed the dominating role of pathogens and parasites over any of these causes.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Long non-coding RNAs (lncRNAs) are emerging as critical regulators in honeybee physiology, influencing development, behavior, and stress responses. This study investigates the role of lncRNA LOC113219358 in the immune response and neurophysiological regulation of brains. Using RNA interference (RNAi) and RNA sequencing (RNA-seq), we demonstrate that silencing lncLOC113219358 significantly alters the expression of 162 mRNA transcripts, including genes associated with detoxification, energy metabolism, and neuronal signaling.
View Article and Find Full Text PDFBiomolecules
January 2025
Key Laboratory of Efficient Utilization of Non-Grain Feed Resources (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Shandong Provincial Key Laboratory of Animal Nutrition and Efficient Feeding, College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China.
Olfaction mediated by the antennae is a vital sensory modality for arthropods and could be applied as a tool in pest control. The ectoparasitic mite poses a significant threat to the health of the honey bee worldwide and has garnered global attention. To better understand the chemical ecology of this host-parasite relationship, we collected and characterized the volatile organic compounds (VOCs) from and used electroantennography (EAG) to record the responses of honey bee ( and ) antennae to the different VOCs.
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