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Photon mini-GRID therapy for preoperative breast cancer tumor treatment: A treatment plan study.
Med Phys
January 2025
Institut Curie, Université PSL, CNRS UMR3347, Inserm U1021, Signalisation Radiobiologie et Cancer, Orsay, France.
Background: Breast cancer is the leading cause of female cancer mortality worldwide, accounting for 1 in 6 cancer deaths. Surgery, radiation, and systemic therapy are the three pillars of breast cancer treatment, with several strategies developed to combine them. The association of preoperative radiotherapy with immunotherapy may improve breast cancer tumor control by exploiting the tumor radio-induced immune priming.
View Article and Find Full Text PDF[WHO classification of melanocytic tumours].
Dermatologie (Heidelb)
January 2025
MVZ Dermatohistopathologie Heidelberg, Mönchhofstr. 52, 69120, Heidelberg, Deutschland.
Background: The update of the World Health Organisation (WHO) classification of skin tumours has led to new aspects in the classification of melanocytic tumours.
Objectives: Presentation of the classification of melanocytic tumours in light of current clinical, histological and genetic data.
Materials And Methods: Review of the classification of melanocytic neoplasms in the fifth edition of the WHO classification of skin tumours, taking into account current disease concepts.
Advancing diagnostics and disease modeling: current concepts in biofabrication of soft microfluidic systems.
In Vitro Model
June 2024
3B's Research Group, European Institute of Excellence in Tissue Engineering and Regenerative Medicine Headquarters, Parque de Ciência e Tecnologia, I3Bs - Research Institute on Biomaterials, Biodegradable and Biomimetics - University of Minho, Zona Industrial da Gandra - Avepark, Barco, Guimaraes, 4805-017 Portugal.
Soft microfluidic systems play a pivotal role in personalized medicine, particularly in in vitro diagnostics tools and disease modeling. These systems offer unprecedented precision and versatility, enabling the creation of intricate three-dimensional (3D) tissue models that can closely emulate both physiological and pathophysiological conditions. By leveraging innovative biomaterials and bioinks, soft microfluidic systems can circumvent the current limitations involving the use of polydimethylsiloxane (PDMS), thus facilitating the development of customizable systems capable of sustaining the functions of encapsulated cells and mimicking complex biological microenvironments.
View Article and Find Full Text PDFCurrent state and promise of user-centered design to harness explainable AI in clinical decision-support systems for patients with CNS tumors.
Front Radiol
January 2025
Department of Biostatistics & Informatics, Colorado School of Public Health, Aurora, CO, United States.
In neuro-oncology, MR imaging is crucial for obtaining detailed brain images to identify neoplasms, plan treatment, guide surgical intervention, and monitor the tumor's response. Recent AI advances in neuroimaging have promising applications in neuro-oncology, including guiding clinical decisions and improving patient management. However, the lack of clarity on how AI arrives at predictions has hindered its clinical translation.
View Article and Find Full Text PDFTaxonomic history, morphology, evolution, gene pool and stress tolerances of azuki bean and its related wild genetic resources.
Breed Sci
September 2024
Research Center of Genetic Resources, National Agriculture and Food Research Organization, 2-1-2 Kannondai, Tsukuba, Ibaraki 305-8602, Japan.
This review compiles information on the morphology, historical taxonomic treatments, species origin, gene pool concept, geographical and ecological habitats, and stress tolerance of the azuki bean () and related species. Willdenow (1802) first described the azuki bean in the genus , and Ohwi and Ohashi (1969) finally transferred it to the genus . The genus is currently divided into five subgenera: , , , , and .
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