Hepatitis B/D virus infection leads to severe liver disease. HDV infection is not routinely investigated since the diagnosis is based on enzyme immunoassays (EIAs), which are not available in all laboratories. This study investigates the performance of new automated assay for anti HDV Ab detection: LIAISON® XL Murex anti-HDV. HBsAg-positive samples were evaluated for HDV serology using the ETI-AB-DELTAK-2 and the new LIAISON® XL Murex with a concordance of 97.5% and 2.42% discordant results. The discordant specimens reacted negatively with EIA and positively with the new test. Dilutions of HDV-purified antibodies and HDV-positive samples were tested with both assays, showing a lower detection limit for the new assay. In conclusion, LIAISON® XL Murex showed a good concordance with the reference method and allowed a more rapid HDV detection. This new diagnostic tool may be useful for a more efficient approach to the HDV diagnosis and evaluation of HDV epidemiology.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.diagmicrobio.2019.114873 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of the Vitros® Anti-T. cruzi assay for its incorporation into the infection diagnostic algorithm.
Heliyon
December 2024
Microbiology Department, Clinical Laboratory North Metropolitan Area, Germans Trias I Pujol University Hospital, 08916 Badalona, Spain.
Background And Objective: Serological screening for Chagas disease (CD) in Latin American adults living in Europe is a cost-effective strategy for transmission prevention. The World Health Organization recommends two different serological tests including native and recombinant antigens for IgG detection. In Spain, most commercialized native tests require manual processing.
View Article and Find Full Text PDFFirst report on human T-lymphotropic virus 1 infection in a group of transgender women.
Front Public Health
November 2024
Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil.
Article Synopsis
- A study was conducted to determine the prevalence of HTLV-1 infection among transgender women (TGW) in Goiânia City, Brazil, revealing a knowledge gap in existing data on this demographic.
- From a sample of 235 TGW, 1.3% tested positive for HTLV-1, with those positive reporting high-risk sexual behaviors and drug use.
- The findings highlight the urgent need for health programs aimed at TGW to control HTLV-1 and other sexually transmitted infections due to their high-risk behaviors.
Performance Comparison of Four Hepatitis E Antibodies Detection Methods.
Microorganisms
September 2024
Hepatitis Unit, National Center of Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Article Synopsis
- - This study compares the effectiveness of four different tests for detecting Hepatitis E virus (HEV) antibodies: LIAISON MUREX, VIRCLIA, WANTAI, and VIDAS.
- - All tests showed 100% sensitivity for detecting anti-HEV IgM in the acute phase, but there were variations in their sensitivity and specificity during later phases of infection.
- - LIAISON MUREX performed the best overall, especially for detecting acute HEV infections and providing accurate results for anti-HEV IgG antibodies.
Biosynthesis, Structural, Spectroscopic, Photoluminescence, and Antifungal Activity of Ni-doped CeO Nanoparticles.
J Fluoresc
July 2024
Department of Physics, Sathyabama Institute of Science & Technology, Chennai, 600119, India.
Pedalium Murex leaf extract was used in this study to create Nickel-doped Cerium oxide (Ni-CeO) nanoparticles at 3 mol% and 5 mol% molar concentrations. The biosynthesized process was applied for the fabrication of Ni-CeO NPs. The X-ray diffraction method was used to identify their crystal structure.
View Article and Find Full Text PDFMore than just a color: Archaeological, analytical, and procedural aspects of Late Bronze Age purple-dye production at Cape Kolonna, Aegina.
PLoS One
June 2024
Center for Forensic Medicine, Medical University of Vienna, Vienna, Austria.
Excavations in the Eastern Suburb of Bronze Age Aegina Kolonna revealed the destruction deposit of two sequenced Early Mycenaean buildings (phase Late Helladic IIA; 16th century BC). The older building is interpreted as a widely undisturbed production site of purple-dye based on indicative finds such as ceramic sherds containing analyzable quantities of pigment, high amounts of mollusk shells, and a few functional facilities. Chemical analysis by HPLC and malacological determination revealed that the banded dye-murex (Hexaplex trunculus) was used almost exclusively.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!