Using decalcified collagen scaffolds to improve healing after transoral partial glossectomy for squamous cell carcinoma.

Introduction: Transoral partial glossectomy procedures for small squamous cell carcinomas of the anterior tongue often leave significant defects which are challenging to reconstruct. Post-operative scarring leads to adhesions, reduced tongue mobility and limitations of function. We present a series of cases where a decalcified collagen scaffold was successfully used in this challenging reconstructive setting.

Methods: After standard oncological diagnostic and workup, five patients underwent transoral partial glossectomy procedures. Decalcified collagen scaffolds were used to reconstruct the surgical defect using a standard protocol. Demographic and outcome data were collected retrospectively.

Results: The median length of post-operative stay was 5 days. There was no reported post-operative bleeds or infection. Histological margins were clear. Scaffolds remained in situ at 1 week, and functional recovery was apparent at 6 weeks post-procedure.

Discussion: These results suggest such scaffolds could be used as an adjunct to help reconstruct the anterior tongue after oncological resection.

Conclusion: The study supports a call for further exploration and research into the use of these scaffolds as a potentially beneficial avenue for reconstructing the tongue.