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The Global Challenge of : Antimicrobial Resistance and Emerging Intervention Strategies.
Trop Med Infect Dis
January 2025
School of Health and Life Sciences, Teesside University, Middlesbrough TS1 3BX, UK.
Antimicrobial resistance (AMR) in species, particularly and , poses a significant public health threat. These bacteria, which are commonly found in livestock, poultry, companion animals, and wildlife, are the leading causes of foodborne illnesses, often transmitted through contaminated poultry. Extensive exposure to antibiotics in human and veterinary medicine creates selection pressure, driving resistance through mechanisms such as point mutations, horizontal gene transfer, and efflux pumps.
View Article and Find Full Text PDFFrom Natural Hosts to Agricultural Threats: The Evolutionary Journey of Phytopathogenic Fungi.
J Fungi (Basel)
January 2025
School of Life Science and Technology, Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Since the domestication of plants, pathogenic fungi have consistently threatened crop production, evolving genetically to develop increased virulence under various selection pressures. Understanding their evolutionary trends is crucial for predicting and designing control measures against future disease outbreaks. This paper reviews the evolution of fungal pathogens from natural habitats to agricultural settings, focusing on eight significant phytopathogens: , , spp.
View Article and Find Full Text PDFClinical Characteristics and Outcomes in Heart Failure Patients with Implantable Pulmonary Artery Pressure Monitors: A Single Centre Irish Experience.
J Cardiovasc Dev Dis
January 2025
Department of Cardiology, University Hospital Galway, Saolta University Healthcare Group, Newcastle Road, H91YR71 Galway, Ireland.
Hospitalisation for acute decompensated heart failure (HF) portends a poor prognosis. Fluid retention manifesting in dyspnoea and oedema are important clinical features of decompensated heart failure and drive hospital admissions. Intracardiac and pulmonary artery pressure (PAP) monitoring can help predict heart failure decompensation, as changes in these haemodynamics occur before clinical congestion manifests.
View Article and Find Full Text PDFA Review of Sulfate Removal from Water Using Polymeric Membranes.
Membranes (Basel)
January 2025
Industrial Systems Engineering, Produced Water Treatment Laboratory, Faculty of Engineering and Applied Science, University of Regina, Regina, SK S4S 0A2, Canada.
Access to clean and reliable water has become a critical concern due to the global water crisis. High sulfate levels in drinking water raise health concerns for humans and animals and can cause serious corrosion in industrial systems. Sulfated waters represent a major challenge on the Canadian prairies, leading to many cattle deaths.
View Article and Find Full Text PDFProgressive systemic inflammation precedes decompensation in compensated cirrhosis.
JHEP Rep
February 2025
Department of Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Instituto Ramon y Cajal de Investigación Sanitaria (IRYCIS), Universidad de Alcalá, Madrid, Spain.
Background & Aims: Systemic inflammation is a driver of decompensation in cirrhosis with unclear relevance in the compensated stage. We evaluated inflammation and bacterial translocation markers in compensated cirrhosis and their dynamics in relation to the first decompensation.
Methods: This study is nested within the PREDESCI trial, which investigated non-selective beta-blockers for preventing decompensation in compensated cirrhosis and clinically significant portal hypertension (CSPH: hepatic venous pressure gradient ≥10 mmHg).
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