Objective: This study aimed to clarify the association between malnutrition and improvement of swallowing ability during rehabilitation of stroke patients.
Design: This was a retrospective cohort study.
Setting And Participants: One hundred eighty-eight older adults with oropharyngeal dysphagia after stroke who were admitted to a rehabilitation hospital.
Methods: The International Dysphagia Diet Standardization Initiative Functional Diet Scale (IDDSI-FDS) was used to assess swallowing ability. The Global Leadership Initiative on Malnutrition (GLIM) definition was used to diagnose malnutrition. The primary outcome was IDDSI-FDS score at discharge.
Results: The mean age of the patients was 78.9 ± 7.7 years, and 36.7% were women. A total of 122 (64.8%) patients were diagnosed with malnutrition. Compared with those without malnutrition, malnourished patients had more severe dysphagia on admission. After adjusting for confounders, malnutrition was an independent contributor to the IDDSI-FDS scores at discharge (standardized coefficient: -0.165, P = .011).
Conclusion And Implications: In patients with oropharyngeal dysphagia after stroke, malnutrition at admission inversely affected their swallowing ability at discharge. Dysphagia rehabilitation, including early nutritional intervention, may be effective in the recovery of swallowing ability.
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http://dx.doi.org/10.1016/j.jamda.2019.07.008 | DOI Listing |
Virulence
December 2025
Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
The resistance of commonly used clinical antibiotics, such as daptomycin (DAP), has become increasingly serious in the fight against () infection. It is essential to explore key pathogenicity-driven genes/proteins in bacterial infection and antibiotics resistance, which contributes to develop novel therapeutic strategies against infections. The gene of , encoding 5'-nucleotidase (NT5), is nearly unknown for its function in drug resistance and bacterial infection.
View Article and Find Full Text PDFTher Adv Neurol Disord
January 2025
Department of Neurology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei 230601, China.
Background: Dysphagia is a common complication following intracerebral hemorrhage (ICH) and is associated with an increased risk of aspiration pneumonia and poor outcomes.
Objectives: This study aimed to explore associated lesion patterns and contributing factors of post-ICH dysphagia, and predict dysphagia outcomes following ICH.
Design: A multicenter, prospective study.
Behav Brain Res
March 2025
Department of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China. Electronic address:
The discovery of the brain's mirror neuron system enables researchers to gain a deeper understanding of social cognitive activities from the level of neural mechanisms. Mirror neurons are situated in bilateral brain regions, overlapping with the swallowing neural network, and there are complex network pathways connecting the two. Repeatedly inducing the activation of mirror neurons in stroke patients can enhance the brain's ability to relearn its original swallowing function, and then restore the swallowing neural network.
View Article and Find Full Text PDFJ Clin Med
December 2024
Doctoral Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
: Swallowing dysfunction is a prevalent but often overlooked problem in long-term care facilities. This study investigated the relationships between nutritional deficits, frailty, oral health, and swallowing dysfunction. Additionally, we explored the associations between oral muscle weakness, frailty markers, and swallowing dysfunction.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Department of Electrical and Computer Systems Engineering, Monash University, Melbourne, VIC 3800, Australia.
Conventional endoscopy is limited in its ability to examine the small bowel and perform long-term monitoring due to the risk of infection and tissue perforation. Wireless Capsule Endoscopy (WCE) is a painless and non-invasive method of examining the body's internal organs using a small camera that is swallowed like a pill. The existing active locomotion technologies do not have a practical localization system to control the capsule's movement within the body.
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