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Ultrasound-guided laser ablation versus surgery for solitary papillary thyroid microcarcinoma: a retrospective study. | LitMetric

AI Article Synopsis

  • This study compares clinical outcomes of ultrasound-guided laser ablation (LA) and traditional surgery for solitary papillary thyroid microcarcinoma (PTMC) using data from 81 patients, 36 of whom received LA and 45 underwent surgery.
  • The results showed that LA had shorter procedure times and hospital stays, with significant reductions in size and volume of tumors after treatment, while complication and recurrence rates were comparable between both groups.
  • The findings suggest that ultrasound-guided LA is a safe and effective alternative for patients who cannot undergo surgery for PTMC.

Article Abstract

To compare the clinical outcomes of ultrasound-guided laser ablation (LA) and surgery for treatment of solitary papillary thyroid microcarcinoma (PTMC). A total of 81 consecutive patients with solitary PTMC were included in this retrospective study. Among them, 36 received LA and 45 underwent surgery. Surgery was performed by hemithyroidectomy with unilateral central neck dissection. The follow-up consisted of a physical examination, neck ultrasonography, chest X-ray or CT scan and thyroid function tests. The procedure time, hospital stay, complication and recurrence rates were compared between the two groups after treatment. The follow-up period for the LA and surgical group were 49.2 ± 4.5 months (range, 30-54 months) and 48.5 ± 6.2 months (range, 24-54 months), respectively. The mean hospital stay and procedure time in the LA group were shorter than those in the surgical group. After LA, the largest diameter and average volume decreased from 4.7 ± 1.4 mm to 0.2 ± 0.8 mm, and from 43.2 ± 38.8 mm to 0.7 ± 4.1 mm ( < .05 for both), respectively. The complication rates and recurrence rates did not differ between the LA group (2.8% [1 of 36] and 5.6% [2 of 36]) and the surgical group (6.7% [3 of 45] and 6.7% [3 of 45]) ( > .05 for both). No distant metastasis occurred in the either group during the follow-up period. Compared with hemithyroidectomy with unilateral central neck dissection, ultrasound-guided LA was also a safe and effective therapy for treating solitary PTMC, and it may be considered as a treatment alternative for patients who are ineligible or refusal to undergo surgery.

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Source
http://dx.doi.org/10.1080/02656736.2019.1649475DOI Listing

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