Green tea intake is generally recognized as an effective supplement that promotes mental clarity and cognitive function. These health benefits of green tea have been attributed mainly to its effective component, epigallocatechin gallate (EGCG). Because various catechin derivatives potently enhance these health benefits, we manipulated the extraction process with a high-temperature intervention. High-temperature-processed green tea extract (HTP-GTE) showed an elevated proportion of gallocatechin gallate (GCG) content. To investigate the preventive effects of HTP-GTE on cognitive decline, we found its neuroprotective effects against amyloid β (Aβ)-induced neurotoxicity in neurons and clarified that GCG significantly inhibited Aβ aggregation . Moreover, we showed that HTP-GTE intake attenuated several cognitive-decline phenotypes in a model mouse of Alzheimer's disease. These beneficial effects of HTP-GTE against cognitive decline were due to the distinctive composition of the extract and suggest the possibility that HTP-GTE supplementation could attenuate cognitive decline of Alzheimer's disease.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/09168451.2019.1659721 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Appearance of green tea compounds in plasma following acute green tea consumption is modulated by the gut microbiome in mice.
Microbiol Spectr
January 2025
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, Colorado, USA.
Unlabelled: Studies have suggested that phytochemicals in green tea have systemic anti-inflammatory and neuroprotective effects. However, the mechanisms behind these effects are poorly understood, possibly due to the differential metabolism of phytochemicals resulting from variations in gut microbiome composition. To unravel this complex relationship, our team utilized a novel combined microbiome analysis and metabolomics approach applied to low complexity microbiome (LCM) and human colonized (HU) gnotobiotic mice treated with an acute dose of powdered matcha green tea.
View Article and Find Full Text PDFEfficacy of Methylene Blue Thoracic Paravertebral Block in Postoperative Pain After VATS Lobectomy.
Ann Thorac Surg Short Rep
June 2024
Thoracic Surgery Unit, University of Campania Luigi Vanvitelli, Naples, Italy.
Background: Paravertebral block (PVB) is effective in controlling postoperative pain after video-assisted thoracoscopic surgery (VATS) lobectomy but is subject to a high rate of failure because of incorrect site of injection. We compared methylene blue PVB with thoracic epidural anesthesia (TEA) for postoperative pain after VATS lobectomy.
Methods: We conducted a prospective randomized trial of patients undergoing VATS lobectomy; 120 patients were randomly assigned to the PVB or TEA group.
Crucial Role of Aluminium-Regulated Flavonol Glycosides (F2-Type) Biosynthesis in Lateral Root Formation of Camellia sinensis.
Plant Cell Environ
January 2025
State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei, China.
In acidic soil conditions, aluminium (Al) limits crop growth and yields but benefits the growth of tea plants. Flavonols are suggested to form complexes with Al, enhancing Al accumulation in tea plants. The role of flavonols in promoting lateral root formation under Al stress remains unclear.
View Article and Find Full Text PDFMuslim Religious Officials Have Less Voice Training and Higher Rate of Voice Disorder Than Christian Religious Officials.
J Voice
January 2025
Voicest Clinic, Istanbul, Turkiye.
Purpose: To compare the Voice Handicap Index-10 Scores, voice hygiene habits, and voice training of Christian and Muslim religious officials living in Turkiye.
Method: In this study, a mixed method, including quantitative and qualitative research, was used. The population of the research consists of Christian and Muslim religious officials working in Turkiye.
Improving flavor of Wuyi rock tea processed from rain-soaked leaves by optimizing withering conditions.
Food Chem
January 2025
Anxi College of Tea Science, College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Tea Green Cultivation and Processing Collaborative Innovation Center, Fujian Agriculture and Forestry University, Fuzhou 350002, China. Electronic address:
Rainy weather restricts the formation of high-quality Wuyi rock tea (WRT). Herein, an optimized withering process for rain-soaked leaves was developed using response surface methodology. Results showed that increasing the withering temperature, relative humidity, and withering time from 25 °C to 40 °C, 80 % to 97 %, and 3 to 6 h, respectively, effectively improved the sensory qualities of the optimized primary WRT (WRTO) prepared from rain-soaked leaves compared with those before optimization.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!