We review the potential of Amazon forest as a source for circulation and maintenance of native arboviruses as well its capacity to host exotic arboviruses introduced in Brazil during their process of adapting to the Amazon environment. After a brief introduction about arboviruses isolated in Amazon region and description of the main arboviruses pathogenic to humans, we highlight the history of the last two exotic viruses introduced in Brazil - Chikungunya virus (CHIKV) and Zika virus (ZIKV) - and their consequences to the public health. Finally, we discuss and hypothesize what will happen with them after the outbreak. We look to the past to predict the future.
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http://dx.doi.org/10.1590/0001-3765201920190407 | DOI Listing |
Discov Nano
January 2025
Nuclear and Energy Research Institute, IPEN, CNEN/SP, Av. Prof. Lineu Prestes, 2242, São Paulo, SP, CEP05508-000, Brazil.
Gold nanoparticles are widely used in biomedical applications due to their unique properties. However, traditional synthesis methods generate contaminants that cause cytotoxicity and compromise the biocompatibility of the nanomaterials. Therefore, green synthesis methods are essential to produce pure and biocompatible nanoparticles, ensuring their effectiveness in biomedical applications.
View Article and Find Full Text PDFFront Neurosci
January 2025
Graduate Program in Electrical Engineering, Federal University of Pará - UFPA, Belém, Brazil.
Introduction: Wavelet thresholding techniques are crucial in mitigating noise in data communication and storage systems. In image processing, particularly in medical imaging like MRI, noise reduction is vital for improving visual quality and accurate analysis. While existing methods offer noise reduction, they often suffer from limitations like edge and texture loss, poor smoothness, and the need for manual parameter tuning.
View Article and Find Full Text PDFACS Phys Chem Au
January 2025
Modeling and Molecular Simulation Group, São Paulo State University (UNESP), School of Sciences, Bauru 17033-360, Brazil.
This study introduces the penta-structured semiconductor p-CGeP through density functional theory simulations, which possesses an indirect band gap transition of 3.20 eV. Mechanical analysis confirms the mechanical stability of p-CGeP, satisfying Born-Huang criteria.
View Article and Find Full Text PDFACS Omega
January 2025
Federal University of Espírito Santo, Av Marechal Campos 1468, Vitória, ES 29.040 090, Brazil.
Monodisperse and colloidally stable magnetic iron oxide nanoparticles have been developed for diverse biotechnology applications. Although promising for the adsorption of organic molecules, the low density of adsorption sites in these nanoparticles has been a significant challenge. In this study, an optimized factorial design with response surface methodology (RSM) was employed to produce small Superparamagnetic Iron Oxide Nanoparticles (SPIONs) stabilized with tetraethoxysilane (TEOS).
View Article and Find Full Text PDFJ Infect
January 2025
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
Background: Pneumococcal conjugate vaccines (PCVs) introduced in childhood national immunization programs lowered vaccine-type invasive pneumococcal disease (IPD), but replacement with non-vaccine-types persisted throughout the PCV10/13 follow-up period. We assessed PCV10/13 impact on pneumococcal meningitis incidence globally.
Methods: The number of cases with serotyped pneumococci detected in cerebrospinal fluid and population denominators were obtained from surveillance sites globally.
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