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Practical Method for Preparation of ()-2-Amino-5,5,5-trifluoropentanoic Acid via Dynamic Kinetic Resolution. | LitMetric
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Practical Method for Preparation of ()-2-Amino-5,5,5-trifluoropentanoic Acid via Dynamic Kinetic Resolution.

Haibo Mei Jianlin Han Ryosuke Takeda Tsubasa Sakamoto Toshio Miwa Yutaka Minamitsuji Hiroki Moriwaki Hidenori Abe Vadim A Soloshonok

ACS Omega

Department of Organic Chemistry I, Faculty of Chemistry, University of the Basque Country UPV/EHU, Paseo Manuel Lardizábal 3, San Sebastián 20018, Spain.

Published: July 2019

This work reports an operationally convenient ∼20 g scale synthesis of ()-2-amino-5,5,5-trifluoropentanoic acid and its Fmoc-derivative via dynamic kinetic resolution of the corresponding racemate.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682081PMC
http://dx.doi.org/10.1021/acsomega.9b01537DOI Listing

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