[This corrects the article DOI: 10.1021/acsomega.8b00147.].
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http://dx.doi.org/10.1021/acsomega.8b00578 | DOI Listing |
Radiographics
February 2025
From the Departments of Radiology and Imaging Sciences (A.M.G., P.J.W., A.M.K.) and Obstetrics and Gynecology (S.E.D.), University of Utah Health, 30 N Mario Capecchi Dr, Salt Lake City, UT 84112; and University of Utah School of Medicine, Salt Lake City, Utah (J.N.C.).
Hydrocephalus is an imprecise term and refers to the imbalance of brain parenchyma and cerebral spinal fluid in the cranial vault. Ventriculomegaly, or enlargement of the ventricular system, is often the more precise term and is therefore preferred. Appropriate imaging and measurement techniques are critical to detect ventriculomegaly and grade its severity.
View Article and Find Full Text PDFAllergol Immunopathol (Madr)
January 2025
Regional Center for Allergy and Clinical Immunology, University Hospital "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico;
Objective: Allergic rhinitis (AR) is highly prevalent worldwide. Good patient adherence ensures successful treatment. This study aimed to identify the association between the intranasal aerosol technique and symptom improvement.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.
Background: The spread of tau in Alzheimer's Disease (AD) can be tracked in vivo using [F-18]MK6240, a PET radioligand that binds to tau aggregates in AD with high affinity. However, significant MK6240 signal is also observed in the meninges and sinus and the extra cerebral binding (ECB) signal from these regions can spill into exterior brain regions complicating evaluation of early stage AD tauopathy. This study evaluates the magnitude and variability of ECB in a large imaging cohort to identify trends in this signal.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.
Background: Highly specific ATN plasma biomarker assays for neurodegenerative diseases have been developed, but their associations with cognition vary in different populations. Kidney disease, common in diabetes, may decrease the predictive precision of those biomarkers. The aim of this study was to characterize for the first time the relationships between plasma ATN biomarkers and cognitive function in adults with T1D.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Memory and Aging Center, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Background: Physical activity (PA) is associated with lower dementia risk; however, underlying molecular pathways are poorly understood. We leveraged large-scale plasma proteomics to identify biological signatures of objectively-monitored PA in cognitively unimpaired (CU) older adults and cross-validated signatures in independent exercise intervention and Alzheimer's disease (AD) cohorts.
Method: Discovery cohort included 65 CU adults (mean = 76.
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