A facile and efficient route for the synthesis of 2,4-disubstituted imidazoles from benzimidamides and vinyl azides through [3 + 2] cyclization under catalyst-free conditions has been described. The method is compatible for a broad range of functional groups with good to excellent yields.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641739 | PMC |
| http://dx.doi.org/10.1021/acsomega.7b00969 | DOI Listing |
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